PMID: 9160200Apr 1, 1997Paper

Helicobacter pylori infection after partial gastrectomy for peptic ulcer and its role in relapsing disease

European Journal of Gastroenterology & Hepatology
M K LeivonenS F Nordling

Abstract

To elucidate the role of Helicobacter pylori in relapsing disease after partial gastrectomy for peptic ulcer. Retrospective study of gastroscopies between January 1985 and February 1988. Department of Surgery, Helsinki University Central Hospital, Finland. One hundred and fifty-five patients, who had undergone partial gastrectomy for peptic ulcer disease. Correlation between clinical and laboratory data, macroscopic findings at gastroscopy and histopathology. At gastroscopy 41 patients showed an ulcer at the site of anastomosis or in the gastric stump and two patients had a history of a previous ulcer recurrence. The median time interval between operation and relapse was 4 years. There was no correlation between ulcer recurrence, sex, age, ABO blood group or other diseases. Smokers and patients using non-steroidal anti-inflammatory drugs (NSAIDs) or alcohol had more relapses, but the difference was not significant. The recurrence rate was higher after Billroth II (BII; 34%) than after Roux-en-Y (14%; P = 0.03) or Billroth I (BI) reconstruction (24%). Giemsa staining demonstrated H. pylori in the gastric stump of 37% of the patients. H. pylori expression was related to age but unrelated to sex, ABO blood group, NSAID use, smokin...Continue Reading

Citations

Feb 24, 2000·The American Journal of Gastroenterology·A LanasB I Hirschowitz
Aug 10, 2004·World Journal of Gastroenterology : WJG·Christian KirschStephan Miehlke
Sep 19, 2007·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·De-Chuan ChanYou-Chen Chao

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