Helicobacter pylori infection and serum ferritin: A population-based study among 1806 adults in Germany

The American Journal of Gastroenterology
G BergH Brenner

Abstract

Helicobacter pylori may possibly affect the iron metabolism by occult bleeding, impaired absorption of non-hem iron, and by scavenging hem iron or ferritin, as some studies have suggested. The aim of this study was to analyze the association between H. pylori infection and serum ferritin, a marker of the body iron stores. In this analysis, we paid particular attention to the role of dietary iron intake and CagA, an established virulence factor of the agent. The analysis is based on a cross-sectional national health and nutrition survey among healthy people in Germany conducted in 1987/1988. The examination included a detailed questionnaire on medical history and lifestyle factors, a 7-day food record, and blood samples. Infection with H. pylori was measured serologically by ELISA and Westernblot. In total, 39.2% of 1806 persons aged 18 to 89 yr included in the study were H. pylori positive, of whom 57.6% had an infection with a CagA-positive H. pylori strain. Age- and sex-adjusted geometric mean of ferritin was 54.5 microg/dl among H. pylori-infected compared with 63.8 microg/dl among uninfected persons. A multiple linear regression model with log-transformed serum ferritin concentration as dependent variable and H. pylori infe...Continue Reading

References

Jun 17, 1995·Lancet·E J KuipersS G Meuwissen
Jun 1, 1993·Infection and Immunity·M O HussonH Leclerc
Mar 1, 1996·Gastroenterology·C C McGowanM J Blaser
Dec 31, 1996·FEMS Immunology and Medical Microbiology·H R AminiT Wadström
Jun 1, 1997·Scandinavian Journal of Gastroenterology·M MarignaniB Annibale
Jul 1, 1997·Scandinavian Journal of Gastroenterology·O GutierrezD Y Graham
Sep 12, 1998·The Medical Journal of Australia·H G PeachS J Farish
Sep 17, 1998·Journal of Clinical Microbiology·R J LaheijA L Verbeek
Apr 27, 1999·Microbiology·D J WorstJ G Kusters
Jul 22, 1999·European Journal of Epidemiology·L I DehneE Hermann-Kunz
Sep 26, 2002·Epidemiology·K J Rothman

❮ Previous
Next ❯

Citations

Aug 13, 2003·Journal of Gastroenterology and Hepatology·Arthur KaffesPeter H Katelaris
Oct 21, 2011·Clinical and Vaccine Immunology : CVI·Thomas WexPeter Malfertheiner
Sep 6, 2003·Journal of Clinical Microbiology·M SörbergM Granström
Aug 31, 2011·Clinical Chemistry and Laboratory Medicine : CCLM·Victor M Cardenas
Sep 30, 2009·World Journal of Gastroenterology : WJG·Fernando Fernández-BañaresMontserrat Forné
Jul 25, 2012·Saudi Journal of Gastroenterology : Official Journal of the Saudi Gastroenterology Association·Soundravally RajendiranAbdoul Hamide
Dec 1, 2004·Alimentary Pharmacology & Therapeutics·J SalgueiroJ Boccio
Aug 17, 2006·Liver International : Official Journal of the International Association for the Study of the Liver·Yoshio SumidaTakeshi Okanoue
Feb 28, 2007·Hematology·M FerraraL Capozzi
Aug 3, 2004·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·C CiacciG Mazzacca
Jul 18, 2002·Journal of Gastroenterology and Hepatology·Jeong Kee SeoKyung Dan Choi
Aug 15, 2003·International Journal of Cancer. Journal International Du Cancer·Nuno Lunet, Henrique Barros
Jul 13, 2007·Birth Defects Research. Part A, Clinical and Molecular Teratology·Marilyn FelknerMark Canfield
Jan 26, 2005·The American Journal of Gastroenterology·Suja DuBois, David J Kearney
Jan 11, 2007·Digestive Diseases and Sciences·Mustafa AkcamReha Artan
Nov 18, 2008·The Journal of Obstetrics and Gynaecology Research·Baris MulayimFiliz F Yanik
Jun 16, 2009·Journal of Pediatric Gastroenterology and Nutrition·Khitam MuhsenDani Cohen
Nov 25, 2005·American Journal of Epidemiology·Victor M CardenasDavid Y Graham
Jan 1, 2014·Archives of Gynecology and Obstetrics·Ehab H Nashaat, Ghada M Mansour
Oct 4, 2014·World Journal of Gastroenterology : WJG·Germán Campuzano-Maya
Jun 4, 2019·Clinical Chemistry and Laboratory Medicine : CCLM·Dietmar EnkoAndreas Meinitzer
Oct 2, 2007·Southern Medical Journal·Ayşegül BabaliSeyfettin Köklü
Jan 22, 2004·Journal of Pediatric Gastroenterology and Nutrition·Gökhan BaysoyEnder Pehlivanoğlu
Apr 18, 2019·Minerva gastroenterologica e dietologica·Elisa Santambrogio, Lorella Orsucci
Aug 29, 2018·Gastroenterology Report·Savio JohnUma Murthy
Jun 13, 2003·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·B AnnibaleG Delle Fave
Nov 1, 2002·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·B AnnibaleG Delle Fave

❮ Previous
Next ❯

Related Concepts

Related Feeds

Anemia

Anemia develops when your blood lacks enough healthy red blood cells. Anemia of inflammation (AI, also called anemia of chronic disease) is a common, typically normocytic, normochromic anemia that is caused by an underlying inflammatory disease. Here is the latest research on anemia.

Atrophic Gastritis

Atrophic Gastritis is a process where gastric glandular cells are lost and replaced with firbous tissues, as a result of chronic inflammation. Learn more about Atrophic Gastritis here.