Helicobacter pylori infection combined with non-alcoholic fatty liver disease increase the risk of atherosclerosis: Focus in carotid artery plaque

Medicine
Lo-Yip YuChuan-Chuan Liu

Abstract

Atherosclerosis has severe consequences on human health. Carotid artery plaques are a condition typically caused by atherosclerosis. Previous studies showed that nonalcoholic fatty liver disease (NAFLD) and Helicobacter pylori (H pylori) are risks factors for carotid artery plaque formation. We hypothesize that the combination of NAFLD with H pylori infection increases the risk of carotid artery plaque formation.A total of 4669 subjects aged > 40 years who underwent routine health checkups between January 2006 and December 2015 were retrospectively reviewed. A serial examination, including abdominal ultrasound, carotid artery ultrasound and esophago-gastroduodenoscopy (EGD), and biopsy urease testing, was conducted.In total, 2402 subjects were enrolled. There were no differences in H pylori infection status among patients with or without NAFLD. There was a trend of more participants with both NAFLD and H pylori infection (number [N]=583) presenting carotid artery plaque (N = 187,32.08%) than participants without NAFLD and H pylori infection (N = 589) who presented plaque formation (N = 106, 18.00%). Participants who had both H pylori infection and NAFLD had the highest risk of any carotid artery plaque (odds ratio [OR], 1.93; 9...Continue Reading

References

May 20, 1996·The American Journal of Medicine·C W Howden
Oct 23, 1997·Clinical Microbiology Reviews·B E DunnM J Blaser
May 29, 1998·Circulation·P W WilsonW B Kannel
Jul 27, 1999·Circulation·S E EpsteinJ Zhu
Oct 25, 2000·The Journal of Immunology : Official Journal of the American Association of Immunologists·F LuzzaF Pallone
Mar 24, 2005·The American Journal of Gastroenterology·Zeki YesilovaKemal Dagalp
May 17, 2005·Current Molecular Medicine·H Yki-Järvinen, J Westerbacka
May 17, 2005·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Giorgio BedogniStefano Bellentani
Feb 1, 2006·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Geoffrey C Farrell, Claire Z Larter
Jan 12, 2008·The American Journal of Medicine·Anna Ludovica FracanzaniSilvia Fargion
Feb 26, 2008·Clinical Immunology : the Official Journal of the Clinical Immunology Society·Xiang ChengYu-Hua Liao
Apr 10, 2009·Current Molecular Medicine·Stergios A PolyzosChristos Zavos
Dec 30, 2009·Hypertension·Meena S MadhurDavid G Harrison
Apr 28, 2010·Journal of Cardiovascular Pharmacology·Richard A Cohen, XiaoYong Tong
Oct 1, 2010·The New England Journal of Medicine·Giovanni TargherEnzo Bonora
Apr 29, 2011·Médecine sciences : M/S·Camille Migdal, Mireille Serres
Apr 13, 2012·European Journal of Gastroenterology & Hepatology·Yasar ColakSafak Kiziltas
Jul 21, 2012·Arteriosclerosis, Thrombosis, and Vascular Biology·Yun HuangGuang Ning
Sep 28, 2012·European Journal of Gastroenterology & Hepatology·Zeynal DoğanErdem Akbal
Sep 10, 2013·Medical Hypotheses·Ludovico AbenavoliMarcello Persico
Nov 14, 2013·World Journal of Gastroenterology : WJG·Meng LiYou-Ming Li
Aug 6, 2014·Journal of Translational Medicine·Giovanni TarantinoGiuseppe Castello
Sep 30, 2014·European Journal of Internal Medicine·Nicoleta V LeachMircea Grigorescu
Oct 14, 2014·World Journal of Gastroenterology : WJG·Silvia FargionAnna Ludovica Fracanzani
Jan 8, 2015·European Journal of Gastroenterology & Hepatology·Jun LuoShuiping Zhao
May 27, 2015·Archives of Medical Research·María Luna-LunaÓscar Pérez-Méndez

❮ Previous
Next ❯

Citations

Apr 30, 2019·Journal of Clinical Gastroenterology·Stergios A Polyzos, Jannis Kountouras
Feb 19, 2020·Molecular Genetics & Genomic Medicine·Abolfazl Zendehdel, Maryam Roham

❮ Previous
Next ❯

Methods Mentioned

BETA
biopsy

Software Mentioned

SAS

Related Concepts

Related Feeds

ApoE, Lipids & Cholesterol

Serum cholesterol, triglycerides, apolipoprotein B (APOB)-containing lipoproteins (very low-density lipoprotein (VLDL), immediate-density lipoprotein (IDL), and low-density lipoprotein (LDL), lipoprotein A (LPA)) and the total cholesterol/high-density lipoprotein (HDL) cholesterol ratio are all connected in diseases. Here is the latest research.

Atherosclerosis Disease Progression

Atherosclerosis is the buildup of plaque on artery walls, causing stenosis which can eventually lead to clinically apparent cardiovascular disease. Find the latest research on atherosclerosis disease progression here.

Carotid Artery Diseases

Carotid artery disease is a group of pathological conditions of the carotid artery. Discover the latest research on carotid artery disease here.