PMID: 11920508Mar 29, 2002Paper

Helicobacter pylori infection in patients with gastric involvement by adult T-cell leukemia/lymphoma

Cancer
Ken OhnitaShigeru Kohno

Abstract

Gastrointestinal involvement is seen frequently in patients with adult T-cell leukemia/lymphoma (ATLL). The authors previously showed a relatively low prevalence of Helicobacter pylori infection in individuals with human T-cell lymphotropic virus 1 (HTLV-1) infection, including patients with ATLL; however, the correlation between H. pylori infection and ATLL gastric involvement has not been investigated. The authors studied 71 patients with ATLL. Gastric involvement was confirmed by endoscopy and biopsy. H. pylori infection was detected by serology, rapid urease test, and immunohistochemistry on biopsy samples. The expression of adhesion molecules on ATLL cells or their ligands on the vasculature in gastric mucosa was analyzed immunohistochemically. The expression of mucosal addressin cell adhesion molecule 1 (MAdCAM-1) was detected by reverse transcriptase-polymerase chain reaction (RT-PCR) analysis. Gastric involvement was detected in 21 patients (30%), including 8 patients with acute clinical subtype ATLL and 13 patients with lymphoma type ATLL. The prevalence of H. pylori infection was 86% (18 of 21 patients) in the patients with gastric involvement but only 38% (19 of 50 patients) in the patients without such involvement (...Continue Reading

References

Apr 1, 1990·The Journal of Infectious Diseases·M J Blaser
Sep 1, 1987·European Journal of Immunology·N Cerf-BensussanC Griscelli
Dec 1, 1980·Proceedings of the National Academy of Sciences of the United States of America·B J PoieszR C Gallo
Oct 1, 1981·Proceedings of the National Academy of Sciences of the United States of America·Y HinumaI Miyoshi
Feb 1, 1995·Leukemia & Lymphoma·T UchiyamaA Imura
Oct 1, 1994·Human Pathology·P G Isaacson
Apr 1, 1997·Gastroenterology·A T Axon
Jan 1, 1997·Journal of Clinical Gastroenterology·K HiguchiT Kuroki
Feb 24, 1999·Journal of Gastroenterology and Hepatology·K KusugamiH Kaneko
Jun 12, 1999·Scandinavian Journal of Gastroenterology·H IsomotoS Kohno
Jul 15, 1999·International Journal of Cancer. Journal International Du Cancer·K IkedaS Kohno
Feb 7, 2001·European Journal of Gastroenterology & Hepatology·H IsomotoS Kohno

❮ Previous
Next ❯

Citations

Feb 6, 2007·Modern Rheumatology·Rie TabataTomoko Nagai
Dec 29, 2013·BMC Gastroenterology·Hajime IsomotoKazuhiko Nakao
Jan 6, 2007·International Journal of Cancer. Journal International Du Cancer·Daisuke NagakuboOsamu Yoshie
Aug 27, 2005·American Journal of Epidemiology·Matti LehtinenPentti Koskela
Jul 11, 2003·World Journal of Gastroenterology : WJG·Yong-Bin DingLi Yang
Nov 24, 2019·Virchows Archiv : an International Journal of Pathology·Snjezana DotlicAlexandra Traverse-Glehen

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.