PMID: 18181463Jan 10, 2008Paper

Helicobacter pylori infection rates at a family practice in Pohnpei, Federated States of Micronesia

Pacific Health Dialog
Bryan A Isaac

Abstract

Upper Gastrointestinal Disease (UGID), especially duodenal ulcers, gastric ulcers, and gastritis, are responsible for a significant number of out-patient visits, hospital admissions, and deaths worldwide. The connection between H. pylori and UGID, including gastric cancer, has been well established. H. pylori has also been shown to increase the risk of gastric adenocarcinoma and mucosal associated lymphoid tissue (MALT) tumors by 2-6 fold, and recent declines in rates of gastric cancer in some countries have precisely followed decreases in childhood H. pylori infection rates. We undertook this study because during six years of practice we had observed a very high rate of patients with UGID who were H. pylori positive. A total of 6933 patient visits (not including repeat visits by patients already enrolled) were screened during the study period, of which 403 patients fit the inclusion criteria and agreed to participate Each were tested for H. pylori, using Quidell's QuickVue gII H. pylori Test Kit. Patients found to be positive were treated appropriately with antibiotics. An opportunistically selected control group was used to compare with the case sample of UGID. 99% of this UGID group was positive for H. pylori, compared with ...Continue Reading

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