Helicobacter pylori-related diseases: dyspepsia, ulcers and gastric cancer

Gastroenterología y hepatología
J P Gisbert

Abstract

This article summarizes the main conclusions drawn from the presentations on Helicobacter pylori infection at Digestive Disease Week 2011. In developed countries, the prevalence of H. pylori infection has decreased, but seems to have reached a plateau at a fairly high level. Antibiotic resistance is increasing in several countries. H. pylori eradication does not contribute to the development of gastroesophageal reflux disease or worsen its course. The frequency of idiopathic peptic ulcers seems to be increasing. H. pylori eradication eliminates almost all episodes of peptic ulcer rebleeding; nevertheless, the use of non-steroidal anti-inflammatory drugs or H. pylori reinfection can lead to bleeding recurrence. H. pylori-negative patients with peptic ulcer bleeding more frequently have bleeding recurrences and higher mortality. In each particular population, there is a close correlation between the prevalence of H. pylori infection and the incidence of gastric cancer. H. pylori eradication is associated with a higher and faster healing rate of ulcerous lesions caused by endoscopic submucosal dissection. In patients undergoing endoscopic submucosal dissection for early gastric cancer, H. pylori eradication decreases the incidence...Continue Reading

References

Nov 26, 1999·Digestive Diseases and Sciences·J P GisbertJ M Pajares
May 29, 2002·Alimentary Pharmacology & Therapeutics·J P Gisbert, J M Pajares
Feb 4, 2006·The American Journal of Gastroenterology·Javier P GisbertUNKNOWN H. pylori Study Group of the Asociación Española de Gastroenterología
Jun 20, 2008·The American Journal of Gastroenterology·Jordi Sánchez-DelgadoManuel Castro
Aug 27, 2009·Alimentary Pharmacology & Therapeutics·J P Gisbert, X Calvet
Jan 8, 2010·Journal of Clinical Gastroenterology·Javier P GisbertColm A O'Morain

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Citations

Jan 16, 2013·Asian Pacific Journal of Cancer Prevention : APJCP·Jiang-Wei XiaoChong-Shu Wang

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