Hemangioma with dabskoid features: a rare histopathologic variant of acquired hemangioma

Journal of Cutaneous Pathology
Mar Llamas-VelascoLuis Requena

Abstract

Dabska tumor, also known as papillary intralymphatic angioendothelioma (PILA), is a locally aggressive hemangiendothelioma characterized by intravascular papillary proliferations of atypical endothelial cells. Besides PILA, papillary tufts lined by hobnail endothelial cells have been rarely described in vascular proliferations. We report two cases of acquired hemangiomas, which focally showed this finding. We present a 15-year-old male and a 7-year-old girl with erythematous nodules. Both lesions were composed of capillary lobules intermingled with large sinusoidal spaces lined with a single layer of flat endothelial cells, which focally developed intravascular papillary proliferations lined by plump hyperchromatic endothelial cells and a central connective tissue core. Both types of cells were positive with CD31 and ERG and negative for Lyve-1, Prox-1 and podoplanin. Wilm's tumor 1 marker was strongly positive in the capillary hemangioma areas while negative in the intravascular tufts. Both lesions recurred after the first excision but we did not observe further recurrence or evidence of metastasis in the follow-up. In summary, our cases expand the histopathologic findings that may be seen in conventional acquired capillary he...Continue Reading

References

Jun 1, 1996·The American Journal of Dermatopathology·E QuecedoA Aliaga
Feb 23, 2002·The American Journal of Surgical Pathology·Luis RequenaJosé Luis Rodríguez-Peralto
Jul 27, 2012·Pediatric Neurosurgery·M RumanaA Ramzan
Jan 19, 2013·Seminars in Diagnostic Pathology·Luis Requena, Heinz Kutzner

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Citations

Nov 3, 2016·Journal of Cutaneous Pathology·María-Teresa Fernández-Figueras, Francisco-José López-Gil
Jul 15, 2016·The American Journal of Dermatopathology·Giovanni PaolinoPietro Donati
Mar 25, 2017·The Anatomical Record : Advances in Integrative Anatomy and Evolutionary Biology·Lucio Díaz-FloresJuan F Madrid

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