Hematinic deficiencies and anemia statuses in anti-gastric parietal cell antibody-positive or all autoantibodies-negative erosive oral lichen planus patients

Journal of the Formosan Medical Association = Taiwan Yi Zhi
Julia Yu-Fong ChangAndy Sun

Abstract

Approximately 27% of erosive oral lichen planus (EOLP) patients have serum anti-gastric parietal cell antibody (GPCA) positivity. This study assessed whether serum GPCA or EOLP itself was a significant factor that caused hematinic deficiencies and anemia statuses in GPCA-positive or autoantibodies-negative EOLP patients (GPCA+/EOLP and Abs-/EOLP patients). The mean corpuscular volume (MCV) and mean blood hemoglobin (Hb), iron, vitamin B12, and folic acid levels were measured and compared between any two of three groups of 41 GPCA+/EOLP patients, 198 Abs-/EOLP patients, and 184 healthy control subjects. GPCA+/EOLP patients had significantly lower mean Hb, iron (for women only), and vitamin B12 level as well as significantly greater frequencies of Hb, iron, and vitamin B12 deficiencies than healthy control subjects. Moreover, GPCA+/EOLP patients had significantly lower serum vitamin B12 level and significantly higher MCV as well as a significantly greater frequency of vitamin B12 deficiency than Abs-/EOLP patients. Furthermore, Abs-/EOLP patients did have significantly lower mean Hb, MCV, iron (for women only), vitamin B12, and folic acid levels as well as significantly greater frequencies of Hb and iron deficiencies than healthy...Continue Reading

Citations

Jun 14, 2020·Biological Trace Element Research·Narges Gholizadeh, Nafiseh Sheykhbahaei
Jul 7, 2019·Journal of the Formosan Medical Association = Taiwan Yi Zhi·Chun-Pin ChiangAndy Sun
Jul 22, 2019·Journal of the Formosan Medical Association = Taiwan Yi Zhi·Chun-Pin ChiangAndy Sun
Feb 10, 2019·Journal of the Formosan Medical Association = Taiwan Yi Zhi·Chun-Pin ChiangAndy Sun
Sep 6, 2020·Journal of the Formosan Medical Association = Taiwan Yi Zhi·Meng-Ling ChiangAndy Sun
Mar 21, 2021·International Journal of Oral and Maxillofacial Surgery·F Agha-HosseiniM-S Moosavi
Sep 18, 2020·Journal of Oral Biology and Craniofacial Research·Shantala R NaikAnjani Kumar Shukla

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