Hematopoietic stem cell quiescence: yet another role for p53

Cell Stem Cell
Ronald van OsBrad J Dykstra

Abstract

p53, sometimes referred to as the "guardian of the genome," helps regulate cell-cycle arrest, DNA-damage repair, apoptosis, and senescence. Adding to this list, in this issue of Cell Stem Cell, Liu et al. (2009) show that p53 also plays a role in regulating hematopoietic stem cell quiescence.

References

May 10, 2000·Neuroscience Research·K Yoshikawa
Jan 10, 2002·Nature·Stuart D TynerLawrence A Donehower
Jun 28, 2003·Experimental Hematology·Michael TeKippeJichun Chen
Jan 23, 2004·Nature Reviews. Cancer·Ricardo PardalSean J Morrison

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Citations

Sep 25, 2012·Expert Opinion on Therapeutic Targets·Varun V PrabhuWafik S El-Deiry
Oct 30, 2010·Blood·Joonseok ChoByeong Chel Lee
Aug 17, 2010·Blood·Christine RaguVirginie Penard-Lacronique
Dec 23, 2014·PloS One·Shiva MarthandanStephan Diekmann
Jun 24, 2010·Current Opinion in Hematology·James D PhelanH Leighton Grimes
Feb 26, 2016·Frontiers in Biology·Desiree F LeachTaixing Cui

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