Hemichorea in a diabetes mellitus patient following acute ischemic stroke with changes in regional cerebral blood flow

Journal of the Chinese Medical Association : JCMA
Yutaka SuzukiSatoshi Kamei

Abstract

It is not unusual to observe hemichorea in patients with diabetes mellitus, with origins attributable to recent ischemia. Our patient was a 66-year-old female with diabetes mellitus who suddenly developed right hemichorea, mild muscle weakness of the right upper extremity, ideational apraxia, and acalculia. Her blood glucose was 600 mg/dL, and HbA1c was 13.3%. After the patient underwent head magnetic resonance imaging (MRI), a new cerebral infarction was observed in the left frontal lobe, and treatment was started with edaravone and cilostazol. At the same time, insulin treatment was also started for hyperglycemia. The acalculia and ideational apraxia improved approximately 1 week after treatment initiated, and the hemichorea also decreased. ECD-SPECT was performed on admission, and it was observed that blood flow was decreased in the left frontal lobe and striatum, but increased in the thalamus; two weeks later on follow-up ECD-SPECT, blood flow had increased slightly in the left forebrain and striatum, while it had decreased slightly in the thalamus. This suggests that the cause of hemichorea was related to ischemia. When the activity of the pallidum is impaired, it is presumed that the inhibitory activity towards the thalam...Continue Reading

References

Jan 1, 1982·Archives of Internal Medicine·W G RectorH Moses
Jul 1, 1996·Movement Disorders : Official Journal of the Movement Disorder Society·P PantanoV Di Piero
Jun 8, 2001·Movement Disorders : Official Journal of the Movement Disorder Society·S OharaT Hashimoto
Feb 28, 2002·Journal of Neurology, Neurosurgery, and Psychiatry·J S KimS K Chung
Oct 24, 2003·Lancet Neurology·Ronald B Postuma, Anthony E Lang
Mar 4, 2006·Journal of Magnetic Resonance Imaging : JMRI·Jaya NathErik Armitano

❮ Previous
Next ❯

Related Concepts

Related Feeds

Brain Ischemia

Brain ischemia is a condition in which there is insufficient blood flow to the brain to meet metabolic demand. Discover the latest research on brain ischemia here.

Basal Ganglia

Basal Ganglia are a group of subcortical nuclei in the brain associated with control of voluntary motor movements, procedural and habit learning, emotion, and cognition. Here is the latest research.

Related Papers

Expert Opinion on Pharmacotherapy
Zaid A Al-QudahAdnan I Qureshi
No to hattatsu. Brain and development
A HamaY Matsushima
Clinical Neuropharmacology
R InzelbergR L Carasso
© 2022 Meta ULC. All rights reserved