Hemiparesis, encephalopathy, and extrapontine osmotic myelinolysis in the setting of hyperosmolar hyperglycemia

Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia
Waldo R GuerreroStephen E Nadeau


Osmotic demyelination syndrome (ODS) is a recognized complication of rapid correction of hyponatremia. However, other medical conditions have been associated recently with the development of ODS in the absence of changes in serum sodium. We present a 23-year-old man who developed left hemiparesis and encephalopathy after treatment of hyperglycemia. MRI demonstrated changes in the splenium of the corpus callosum and the posterior limb of the right internal capsule. This report, together with others, suggests that the full spectrum of lesions of ODS, pontine and extrapontine, can occur in the setting of any rapid change in osmolar state.


Sep 1, 1988·Radiology·G M MillerJ P Whisnant
Jan 1, 1997·Annals of Internal Medicine·R Laureno, B I Karp
Jan 10, 2001·Current Opinion in Neurology·W D Brown
Apr 16, 2003·Journal of Child Neurology·Joshua L Bonkowsky, Francis M Filloux
Aug 19, 2004·Journal of Neurology, Neurosurgery, and Psychiatry·R J Martin
Jun 28, 2008·Annals of Clinical Biochemistry·Grainne O'MalleyAmar Agha
May 19, 2009·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Stephanie A HowardUmberto De Girolami

❮ Previous
Next ❯


Jun 4, 2013·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Halil OnderMehmet Akif Topcuoglu
Feb 25, 2014·Journal of Neurology, Neurosurgery, and Psychiatry·Dimitri RenardGuillaume Taieb
Dec 3, 2014·Neurología : publicación oficial de la Sociedad Española de Neurología·J A Matías-GuiuM Ruiz-Yagüe
Nov 29, 2014·Case Reports in Neurological Medicine·Karla Victoria Rodríguez-VelverRené Rodríguez-Gutiérrez
Nov 10, 2013·The Journal of Emergency Medicine·Azeemuddin AhmedAmy Engelman
Apr 29, 2015·Singapore Medical Journal·Monica SainiRajinder Singh
Dec 10, 2020·Clinical Diabetes and Endocrinology·Koshi KusumotoYoshihiko Nishio
Mar 18, 2021·Curēus·Mojgan JalalzadehDonald Baumstein

❮ Previous
Next ❯

Related Concepts

Related Feeds

Anorexia Nervosa

Anorexia nervosa (AN) is a psychiatric condition characterized by severe weight loss and secondary problems associated with malnutrition. Here is the latest research on AN.