[Hemiparesis in acute lymphoblastic leukemia].

Der Radiologe
M KarremannM Dürken

Abstract

The case of an adolescent female patient with acute lymphoblastic leukemia and stroke-like hemiparesis demonstrates a typical manifestation of methotrexate-induced acute encephalopathy. This rare entity occurs both in children and adults and can result from intrathecal as well as high dose intravenous administration of methotrexate. Diagnosis can confidently be made using cerebral MRI including diffusion-weighted imaging (DWI), so that patients can be informed about the favorable prognosis.

References

Dec 22, 2005·Pediatric Radiology·France ZiereisenCatherine Christophe
Oct 20, 2007·Annals of Oncology : Official Journal of the European Society for Medical Oncology·H InabaN C Daw

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