Hemisphere and Gender Differences in the Rich-Club Organization of Structural Networks

Cerebral Cortex
Bin WangDandan Li

Abstract

Structural and functional differences in brain hemispheric asymmetry have been well documented between female and male adults. However, potential differences in the connectivity patterns of the rich-club organization of hemispheric structural networks in females and males remain to be determined. In this study, diffusion tensor imaging was used to construct hemispheric structural networks in healthy subjects, and graph theoretical analysis approaches were applied to quantify hemisphere and gender differences in rich-club organization. The results showed that rich-club organization was consistently observed in both hemispheres of female and male adults. Moreover, a reduced level of connectivity was found in the left hemisphere. Notably, rightward asymmetries were mainly observed in feeder and local connections among one hub region and peripheral regions, many of which are implicated in visual processing and spatial attention functions. Additionally, significant gender differences were revealed in the rich-club, feeder, and local connections in rich-club organization. These gender-related hub and peripheral regions are involved in emotional, sensory, and cognitive control functions. The topological changes in rich-club organizati...Continue Reading

References

Sep 30, 1998·Current Opinion in Neurobiology·Y Iwamura
Apr 3, 2001·The British Journal of Psychiatry : the Journal of Mental Science·I SommerA Bouma
Jan 5, 2002·Neuroscience Research·K Kansaku, S Kitazawa
Sep 28, 2002·The International Journal of Neuroscience·A Riza ErdoğanSenol Dane
Jan 4, 2003·Nature Reviews. Neuroscience·Arthur W Toga, Paul M Thompson
Jul 26, 2003·NeuroImage·Vassili A KovalevD Yves von Cramon
Apr 15, 2004·Current Opinion in Neurobiology·Marlene BehrmannSarah Shomstein
Apr 30, 2004·Cerebral Cortex·C BüchelM A Koch
Dec 18, 2004·Neuron·Christopher D ChambersJason B Mattingley
Nov 4, 2005·Cerebral Cortex·E LudersA W Toga
May 24, 2006·Brain and Language·A M ClementsL E Cutting
Feb 6, 2007·PLoS Computational Biology·Sophie Achard, Ed Bullmore
Oct 18, 2007·PloS One·Olaf SpornsRolf Kötter
Aug 25, 2009·Brain Imaging and Behavior·Chiang-Shan Ray LiCarolyn M Mazure
Oct 13, 2009·NeuroImage·Mikail Rubinov, Olaf Sporns
Dec 8, 2009·Biological Psychiatry·Lars M RimolAnders M Dale
Mar 12, 2010·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Gordon L ShulmanMaurizio Corbetta
May 27, 2010·Brain Imaging and Behavior·Tadashi InoHidenao Fukuyama
Jan 29, 2011·Journal of Magnetic Resonance Imaging : JMRI·Tianyi YanJinglong Wu
Apr 5, 2011·NeuroImage·Mikail Rubinov, Olaf Sporns
Apr 30, 2011·The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry·Gaolang GongAlan C Evans
May 17, 2011·Cerebral Cortex·Sheng ZhangChiang-shan R Li
May 26, 2011·NeuroImage·Dardo Tomasi, Nora D Volkow
Oct 18, 2011·Cerebral Cortex·Megan M HertingBonnie J Nagel
Nov 4, 2011·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Martijn P van den Heuvel, Olaf Sporns
Dec 20, 2011·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Elkhonon GoldbergThomas Thesen
Mar 24, 2012·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Feng BaiZhijun Zhang
May 24, 2012·The Behavioral and Brain Sciences·Luiz Pessoa
Jun 20, 2012·Proceedings of the National Academy of Sciences of the United States of America·Martijn P van den HeuvelOlaf Sporns
Nov 14, 2012·Current Opinion in Neurobiology·Angela D Friederici, Sarah M E Gierhan
Jan 16, 2013·Proceedings of the National Academy of Sciences of the United States of America·Xia LiangYihong Yang
Jan 16, 2013·Scientific Reports·Rodrigo Aldecoa, Ignacio Marín
Jan 26, 2013·Current Opinion in Neurobiology·Jonathan D Power, Steven E Petersen

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