PMID: 6112285Mar 1, 1981Paper

Hemo- and cardiodynamic changes in arterial hypertension patients as affected by alpha- and beta-adrenergic blockader therapy

Kardiologiia
B Ia Zonis

Abstract

It is shown that treatment of patients with arterial hypertension with obsidan reduces arterial pressure because of a decrease in cardiac output; in treatment with pyroxan the arterial pressure is reduced due to decrease in total peripheral vascular resistance. Combined treatment with alpha- and beta-adrenergic blocking agents allows arterial pressure to be normalized with much lesser doses because the interrelationships of the principal hemodynamic values are normalized.

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