PMID: 8967877Dec 1, 1995Paper

Hemocompatible cellulose dialysis membranes modified with phospholipid polymers

Artificial Organs
Kazuhiko Ishihara, N Nakabayashi

Abstract

Hemocompatibility is one of the most important properties for hemodialysis membranes. For improvement of the hemocompatibility on a cellulose dialysis membrane, modifications with new blood-compatible phospholipid polymers were carried out. These methods included a direct grafting of the phospholipid monomer on the membrane surface, coating the membrane surface with a water-soluble graft copolymer composed of a cellulose backbone and phospholipid polymer as a branch, and covalent bonding with a reactive phospholipid polymer on the membrane surface. These modified membranes could reduce protein adsorption as well as complement activation and platelet adhesion on the surface without any adverse effects on the membrane performance.

References

Dec 1, 1992·Journal of Biomedical Materials Research·K IshiharaN Nakabayashi
Jan 1, 1991·Journal of Biomaterials Science. Polymer Edition·T UedaN Nakabayashi
Nov 1, 1991·Journal of Biomedical Materials Research·K IshiharaJ M Anderson
Aug 1, 1990·Journal of Biomedical Materials Research·K IshiharaN Nakabayashi
Dec 1, 1989·Journal of Biomedical Materials Research·S R Mulzer, J L Brash

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Citations

Aug 1, 2000·Colloids and Surfaces. B, Biointerfaces·A L Lewis
Oct 29, 2000·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·F De SomerG Van Nooten
Feb 13, 2003·Artificial Organs·Shin'ichiro KiharaBartley P Griffith

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