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Hemodynamic and clinical onset in patients with hereditary pulmonary arterial hypertension and BMPR2 mutations

Respiratory Research

Aug 2, 2011

Nicole PfarrE Grünig

Abstract

Mutations in the bone morphogenetic protein receptor 2 (BMPR2) gene can lead to idiopathic pulmonary arterial hypertension (IPAH). This study prospectively screened for BMPR2 mutations in a large cohort of PAH-patients and compared clinical features between BMPR2 mutation carriers and n...read more

Mentioned in this Paper

SRSF5 gene
Biochemical Pathway
Pulmonary Arterial Hypertension
2-oxo-hept-3-ene-1,7-dioate Hydratase Activity
Bone morphogenetic protein receptor type II
Work-up
Mutation, Nonsense
Exons
Lung
Extracellular
36
Paper Details
References
  • References25
  • Citations23
123
  • References25
  • Citations23

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Hemodynamic and clinical onset in patients with hereditary pulmonary arterial hypertension and BMPR2 mutations

Respiratory Research

Aug 2, 2011

Nicole PfarrE Grünig

PMID: 21801371

DOI: 10.1186/1465-9921-12-99

Abstract

Mutations in the bone morphogenetic protein receptor 2 (BMPR2) gene can lead to idiopathic pulmonary arterial hypertension (IPAH). This study prospectively screened for BMPR2 mutations in a large cohort of PAH-patients and compared clinical features between BMPR2 mutation carriers and n...read more

Mentioned in this Paper

SRSF5 gene
Biochemical Pathway
Pulmonary Arterial Hypertension
2-oxo-hept-3-ene-1,7-dioate Hydratase Activity
Bone morphogenetic protein receptor type II
Work-up
Mutation, Nonsense
Exons
Lung
Extracellular
36

Similar Papers Found In These Feeds

Related Papers

Paper Details
References
  • References25
  • Citations23
123
  • References25
  • Citations23
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