PMID: 3383235Jan 1, 1988Paper

Hemodynamic and electrocardiographic consequences of high- and low-osmolality contrast agents for left ventricular angiography

Catheterization and Cardiovascular Diagnosis
H Vik-MoR Danielsen

Abstract

The cardiovascular effects of two nonionic contrast agents with low osmolality (iohexol and metrizamide) were compared with one standard ionic, high-osmolality contrast agent (metrizoate) used for left ventricular (LV) angiography in patients with coronary heart disease. Metrizoate induced a marked elevation of LV end-diastolic pressure and LV systolic pressure and an increase in cardiac output after a delay of a few minutes. All these changes were significantly less severe with iohexol and metrizamide. Hypotension occurring 30 sec after LV angiography was observed only with use of metrizoate. All agents increased heart rate, but the increase after metrizoate was significantly more pronounced and prolonged. The PQ and QT interval was prolonged only by metrizoate. The subjective symptoms were significantly more marked with metrizoate than with the two other agents. Thus the new nonionic contrast agent iohexol and metrizamide produced markedly less hemodynamic and electrocardiographic disturbance than the ionic agent metrizoate.

References

Oct 1, 1978·Radiology·G L WolfK Kilzer
May 1, 1986·Progress in Cardiovascular Diseases·P C HanleyH C Smith
Mar 1, 1969·British Heart Journal·A K BrownN G Doukas
Oct 1, 1966·Circulation·R N MacAlpinW N Hanafee
Jul 1, 1966·The American Journal of Cardiology·H T DodgeR R Hawley
Oct 1, 1984·British Heart Journal·R Hayward, P Dawson
Jan 1, 1983·Catheterization and Cardiovascular Diagnosis·A Theler, H R Baur
Mar 1, 1981·The British Journal of Radiology·D C Cumberland

❮ Previous
Next ❯

Citations

Apr 1, 1991·Catheterization and Cardiovascular Diagnosis·W H Matthai, J W Hirshfeld
Oct 1, 1994·American Heart Journal·E A CaraccioloF V Aguire
May 1, 1992·American Heart Journal·K G LehmannW C Zeldow
Jun 1, 1993·Journal of the American College of Cardiology·N R PoweE P Steinberg
Jul 1, 1989·International Journal of Cardiology·J J GlazierH Gavras
Jul 6, 2000·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·A BergstraH J Crijns
Mar 1, 1989·Catheterization and Cardiovascular Diagnosis·M H HwangP J Scanlon

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.