Abstract
The multiple stent placement technique has largely improved the long-term outcomes of intracranial fusiform aneurysms, but the hemodynamic mechanisms remain unclear. In this study, we analyzed the hemodynamic changes caused by different stent-placement strategies in patient-specific models using the computational fluid dynamics technique, aiming to provide evidence for clinical decision-making. Ten vertebral artery fusiform aneurysms were included, and their patient-specific computational fluid dynamics models were reconstructed. A fast virtual stent placement technique was used to simulate sequential multiple stent placements (from a single stent to triple stents) in the vertebral artery fusiform aneurysm models. Hemodynamic parameters, including wall shear stress, pressure, oscillatory shear index, relative residence time, and flow pattern, were calculated and compared among groups with different numbers of stents. Virtual stents were deployed in all 10 cases successfully, consistent with the real stent configuration. Wall shear stress decreased progressively by 7.2%, 20.6%, and 25.8% as the number of stents increased. Meanwhile, relative residence time and pressure increased on average by 11.3%, 15.4%, and 45.0% and by 15.7%...Continue Reading
References
Dec 1, 1989·Stroke; a Journal of Cerebral Circulation·H C EchiverriM Gujrati
Jan 1, 1997·Neurosurgery·P L PenarT R Tritton
Nov 2, 2005·Journal of Biomechanics·Philippe ThériaultRichard Gallo
Nov 25, 2005·Journal of Neurosurgery·Gádor CantónPeter K Nelson
May 4, 2006·European Radiology·Woong YoonMichael P Marks
Jun 9, 2006·Neurological Research·Tomoki HashimotoWilliam L Young
Apr 2, 2008·Journal of Biomechanics·Tong-Miin Liou, Yi-Chen Li
Jul 16, 2010·Medical Image Analysis·Ignacio LarrabideAlejandro F Frangi
Nov 3, 2010·Annals of Biomedical Engineering·L AugsburgerN Stergiopulos
Nov 13, 2010·AJNR. American Journal of Neuroradiology·J R CebralC M Putman
Jan 5, 2011·World Neurosurgery·Markus TremmelHui Meng
Mar 13, 2012·Journal of Neurosurgery·Adnan H SiddiquiElad I Levy
Mar 26, 2013·Neurologia Medico-chirurgica·Hiroshi TanemuraWaro Taki
Sep 13, 2014·Neurological Research·Yu Sam WonYon Kwon Ihn
Jul 24, 2015·Radiology·Pengfei YangJianmin Liu
Feb 26, 2016·PloS One·Nan LvQinghai Huang
Nov 12, 2016·Journal of Neurointerventional Surgery·P BhogalS Fischer
Citations
Aug 20, 2019·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Andrea N Goldstein-PiekarskiLeanne M Williams
Dec 23, 2019·Sleep & Breathing = Schlaf & Atmung·Binghu JiangZhanhui Gao
Jul 26, 2019·Biomedical Engineering Online·Sergey SindeevBenjamin Friedrich
Jan 15, 2021·Scientific Reports·Woo-Suk TaeSung-Bom Pyun
Feb 11, 2021·Journal of Neurology·Camille K MiltonAndrew K Conner
Mar 3, 2019·World Neurosurgery·Yibin FangJianmin Liu