Hemodynamic changes in arterial feeders and draining veins during embolotherapy of arteriovenous malformations: an experimental study in a swine model

Neurosurgery
Y MurayamaF Viñuela

Abstract

Transcatheter assessment of changes in draining vein (DV) flow velocity has been proposed recently as a potentially useful procedure for hemodynamic monitoring of the progression of embolotherapy in cerebral arteriovenous malformations (AVMs). We compared and contrasted changes in hemodynamic parameters of arterial feeders (AFs) and DVs during experimental AVM embolotherapy. Carotid-jugular fistula-type AVM models were surgically created in eight swine. Pre- and postembolization transcatheter mean AF and DV pressures, DV-time average spectral peak velocity, and AF and DV pulsatility indices were assessed. An expression, the peak systolic velocity minus end-diastolic velocity (Vs - Ved), was also used in evaluating the transvenous Doppler spectra. Pre- and postembolization hemodynamic parameters were compared statistically. Pre-embolization DV flow was pulsatile (Vs - Ved, 12 +/- 4.8 cm/s), with a mean DV velocity of 39.3 +/- 11.4 cm per second. Postembolization, this changed to a less/nonpulsatile pattern (Vs - Ved, 5.4 +/- 2.7 cm/s; P = 0.0035) with a lower mean DV-average spectral peak velocity of 7.0 +/- 3.1 cm per second (P = 0.0001). The mean DV pressure was also reduced from 52.0 +/- 8.2 to 45.5 +/- 8.7 mm Hg (P = 0.0023)...Continue Reading

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Citations

Dec 16, 2005·Neurological Research·Mario N Carvi Y Nievas
Jul 11, 2007·Neurosurgery·Reza JahanFernando Viñuela
Apr 12, 2014·Translational Stroke Research·Wanqiu ChenHua Su
Jan 21, 2014·Journal of Neurointerventional Surgery·Diogo C HaussenMohammad Ali Aziz-Sultan
Dec 20, 2004·Interventional Neuroradiology : Journal of Peritherapeutic Neuroradiology, Surgical Procedures and Related Neurosciences·M Forjaz SeccaA Goulão
Dec 10, 2015·BioMed Research International·Ming XuZhiyong Qin
Feb 27, 2007·Stroke; a Journal of Cerebral Circulation·Italo Linfante, Ajay K Wakhloo
Apr 30, 2014·Neurosurgical Review·Raquel Gutiérrez-GonzálezGregorio Rodríguez-Boto
Oct 5, 2005·Interventional Neuroradiology : Journal of Peritherapeutic Neuroradiology, Surgical Procedures and Related Neurosciences·F ViñuelaY Murayama

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