PMID: 6630771Nov 1, 1983Paper

Hemodynamic changes induced by cardiac angiography with ioxaglate: comparison with diatrizoate

Journal of the American College of Cardiology
J W HirshfeldG L Wolf

Abstract

The hemodynamic and electrocardiographic changes induced by left ventriculography and coronary arteriography with ioxaglate (a new low osmolality angiographic contrast agent) were characterized and compared with the changes induced by a commercial formulation of the commonly used angiographic contrast agent, diatrizoate (Renografin-76). Left ventriculography and coronary arteriography were performed in 25 patients utilizing ioxaglate and in another 25 patients utilizing diatrizoate. Both agents increased left ventricular end-diastolic pressure and decreased arteriovenous oxygen difference after left ventriculography, but the magnitude of the increase caused by ioxaglate was significantly less than that caused by diatrizoate (changes in left ventricular end-diastolic pressure was 5.3 +/- 1.3 mm Hg with ioxaglate and 9.5 +/- 1.5 mm Hg with diatrizoate [p less than 0.02] ). Change in arteriovenous oxygen difference was -0.33 +/- 0.19 ml/100 ml with ioxaglate and -0.85 +/- 0.13 ml/100 ml with diatrizoate (p less than 0.05). Both agents were well tolerated when used for coronary arteriography with no adverse events occurring in either group. Ioxaglate is a well tolerated cardiac angiographic contrast agent that produces less hemodyn...Continue Reading

Citations

Apr 1, 1991·Catheterization and Cardiovascular Diagnosis·W H Matthai, J W Hirshfeld
Feb 1, 1993·Catheterization and Cardiovascular Diagnosis·J H PiessensJ L Willems
Jun 1, 1993·Journal of the American College of Cardiology·N R PoweE P Steinberg
Feb 1, 1985·Journal of the American College of Cardiology·E W GertzC Hu
Jul 6, 2014·Seminars in Dialysis·Sana F Khan, Kambiz Kalantari
Sep 1, 1985·American Heart Journal·J A WisneskiD L Morris
May 1, 1986·Progress in Cardiovascular Diseases·P C HanleyH C Smith
Nov 15, 1990·The American Journal of Cardiology·J L VacekG D Beauchamp
Nov 28, 2002·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·Enrique EsplugasFrancisco Jara
Dec 15, 2015·Annals of Biomedical Engineering·J T J HonkanenJ Töyräs
Mar 1, 1989·Catheterization and Cardiovascular Diagnosis·Z E PiaoP J Scanlon
Jan 1, 1988·Catheterization and Cardiovascular Diagnosis·R F DaviesB Larocque

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiology Journals

Discover the latest cardiology research in this collection of the top cardiology journals.