PMID: 640085Feb 1, 1978Paper

Hemodynamic changes upon nociceptive stimulation and stimulation of the amygdaloid complex following catecholamine administration

Fiziologicheskiĭ zhurnal SSSR imeni I. M. Sechenova
L S Isakova, G E Danilov

Abstract

In cats, changes in arterial pressure (AP), intracardiac pressure (ICP), and blood flow volume rate following a nociceptive stimulus, stimulation of the amygdala and the combination of these before and after adrenaline (A) and norepinephrine (NE) administration into the lateral nucleus of amygdala, were studied. Nociceptive stimuli and electric stimulation of amygdala increased AP and ICP. The combination of these increased the pressor reaction. The blood flow volume rate was not altered by the nociceptive stimulus while decreasing at amygdalar stimulation. After A and NE administration the stimulation of amygdala plus the nociceptive stimulus suppressed the pressor reaction; a nociceptive stimulus was followed by the same changes as in intact cats; a nociceptive stimulus plus the stimulation of the amygdala increased the pressor reaction. The blood flow volume rate response to the stimuli was the same as in the control group. But the stimulation of amygdala after NE and a nociceptive stimulus plus amygdala stimulation (20 min after A) increased the blood flow volume rate, while the stimulation of amygdala alone with A administration reduced the blood flow.

Related Concepts

Related Feeds

Amygdala and Midbrain Dopamine

The midbrain dopamine system is widely studied for its involvement in emotional and motivational behavior. Some of these neurons receive information from the amygdala and project throughout the cortex. When the circuit and transmission of dopamine is disrupted symptoms may present. Here is the latest research on the amygdala and midbrain dopamine.

Amygdala: Sensory Processes

Amygdalae, nuclei clusters located in the temporal lobe of the brain, play a role in memory, emotional responses, and decision-making. Here is the latest research on sensory processes in the amygdala.