Hemodynamic differences between Pipeline and coil-adjunctive intracranial stents

Journal of Neurointerventional Surgery
Brian Thomas JankowitzJohn Michael Wainwright

Abstract

Modern coil-adjunctive intracranial stent designs have increased metal surface coverage to construct putative 'flow diverter lights.' This is rooted in the assumption that flow diversion is linearly correlated with metal surface coverage rather than being a threshold to be reached by device porosity and design. To evaluate this assumption, by performing computational flow analysis on three aneurysm models treated with low metal surface coverage stents (ATLAS and Enterprise), a Pipeline flow diverter, and the LVIS Blue stent. Computational flow analysis was performed on virtual deployment models entailing deployment of an ATLAS, Enterprise, LVIS Blue, or Pipeline. The impact of device deployment on velocity vectors at the neck, maximum wall shear stress, inflow rate into the aneurysm, and turnover time was determined. Velocity vector plots demonstrated low magnitude, localized inflow jets for Pipeline only; asymmetric, selectively high inflow jets were seen for LVIS Blue, and broader velocity vector clusters were seen for Atlas and Enterprise. Reduction in wall shear stress as compared with baseline was significant for all devices and greatest for the Pipeline. Mean peak wall shear stress was significantly lower for LVIS Blue in...Continue Reading

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Aug 6, 2018·Journal of Neurointerventional Surgery·Bradley A GrossBrian Thomas Jankowitz

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Citations

Aug 25, 2020·Interventional Neuroradiology : Journal of Peritherapeutic Neuroradiology, Surgical Procedures and Related Neurosciences·Zhongbin TianJian Liu
Jun 19, 2021·Interventional Neuroradiology : Journal of Peritherapeutic Neuroradiology, Surgical Procedures and Related Neurosciences·Hyun Ho ChoiMoon Hee Han
Jun 15, 2021·Interventional Neuroradiology : Journal of Peritherapeutic Neuroradiology, Surgical Procedures and Related Neurosciences·Jennifer Ayers-RinglerRamanathan Kadirvel
Nov 17, 2021·International Journal for Numerical Methods in Biomedical Engineering·Xiaojian QiuYuanyuan Li

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