Hemodynamic effect of the left gastric artery on esophageal varices in patients with cirrhosis

Journal of Gastroenterology
Soichiro KiyonoOsamu Yokosuka

Abstract

To examine the hemodynamic effect of the left gastric artery (LGA) on the esophageal varices (EV) in cirrhosis. This was a prospective study performed in 48 cirrhosis patients (35 men, 13 women; median age 61.6 ± 11.3 years, range 38-83 years) with EV (medium 35, large 13), who underwent selective LGA angiography, hepatic venous catheterization, endoscopic ultrasonography (EUS) and Doppler ultrasonography before endoscopic treatment for EV. Angiographic findings including diameter of the main trunk, detection time of EV, and mild/severe degree of peripheral staining were assessed. The median period of post-treatment observation was 17.1 months. LGA angiograms were successfully obtained in 45/48 patients. EV were demonstrated in 45/45 patients, with a mean detection time of 6.9 s (2-21), which was longer in patients with variceal recurrence (7.0 s) than in those without (5.6 s, P = 0.480). The staining was mild in 25 patients (55.6 %) and severe in 20 patients (44.4 %), and portal hypertensive gastropathy was more frequent in the latter (13/20, 65.0 %) than in the former (7/25, 28.0 %, P = 0.013). Multivariate analysis showed that pre-treatment detection time (P = 0.04) and post-treatment submucosal vascular area at the cardia w...Continue Reading

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Citations

Oct 9, 2016·Obesity Surgery·Nickolas KipshidzeZurab Kakabadze
Jan 14, 2017·World Journal of Hepatology·Dmitry Victorovich GarbuzenkoDmitry Vladimirovich Belov
Dec 2, 2020·Diagnostics·Kazunori NagashimaMakoto Iijima

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