PMID: 6966455Jan 1, 1980Paper

Hemodynamic effects of parenteral and oral mexiletine

Acta cardiologica. Supplementum
M RenardR Bernard

Abstract

Intravenous mexiletine (250 mg in 10 min) given to patients at the acute stage of a myocardial infarction was responsible of a mild decrease of the left ventricular function; two of our patients presented bradycardia with hypotension, immediately corrected by atropine (i.v.). Adverse hemodynamic effects are seldom reported after oral administration.

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