Hemodynamic Performance and Durability of Mosaic Bioprostheses for Aortic Valve Replacement, up to 13 Years

Circulation Journal : Official Journal of the Japanese Circulation Society
Yorihiko MatsumotoJunjiro Kobayashi

Abstract

This study evaluated the mid to long-term durability and hemodynamics of the small-size Mosaic bioprosthesis, a third-generation stented porcine bioprosthesis, for aortic valve replacement (AVR). From 2000 to 2012, 207 patients (117 women; age, 74±8 years; body surface area, 1.48±0.25 m(2)) underwent AVR with a Mosaic bioprosthesis. The mean follow-up period was 3.5±2.7 years (maximum, 12.4 years) and the follow-up rate was 93.7%. A 19-, 21-, 23-, 25-, and 27-mm prosthesis was used in 103, 53, 35, 13, and 3 patients, respectively. The measured effective orifice area was 1.17±0.25, 1.29±0.19, 1.39±0.24, and 1.69 cm(2)for the 19-25 mm prostheses, and the mean transvalvular pressure gradient was 19.4±6.0, 18.5±5.8, 16.5±7.3, and 13.2±2.9 mmHg, respectively. The left ventricular mass regression was significant (P<0.05) with rates of 74.6±18.8%, 75.5±30.2%, 68.1±30.5%, 55.9±12.9%, and 49.2%, respectively. The 30-day mortality rate was 1.9% and the 5- and 10-year actuarial survival rates were 86.0% and 73.7%, respectively. Valve-related comorbidities occurred in 3 patients (structural valve deterioration [SVD] in 1 after 7.2 years, and prosthetic valve endocarditis in 2). Freedom from SVD at 10-year was 96.7%. The mid to long-term pe...Continue Reading

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Citations

Jun 30, 2015·Circulation Journal : Official Journal of the Japanese Circulation Society·Kazuki MorimotoTomoyuki Fujita
Nov 14, 2017·Circulation Journal : Official Journal of the Japanese Circulation Society·Kizuku YamashitaJunjiro Kobayashi
Jan 24, 2018·Circulation·Danny DvirUNKNOWN VIVID (Valve in Valve International Data) Investigators
Dec 6, 2018·JAMA Cardiology·Benish FatimaSamir Kapadia
Jul 25, 2019·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Naoto FukunagaTadaaki Koyama
Jun 20, 2020·Circulation Journal : Official Journal of the Japanese Circulation Society·Yasushi YoshikawaYoshiki Sawa
Jan 31, 2017·Circulation Journal : Official Journal of the Japanese Circulation Society·Yuta KumeJunjiro Kobayashi
Oct 10, 2018·Circulation Journal : Official Journal of the Japanese Circulation Society·Kizuku YamashitaJunjiro Kobayashi
Mar 12, 2021·Interactive Cardiovascular and Thoracic Surgery·Giovanni A ChiarielloIssam Abouliatim
Aug 12, 2021·Interactive Cardiovascular and Thoracic Surgery·Augustijn MorteléKatrien François
Sep 17, 2021·Circulation Journal : Official Journal of the Japanese Circulation Society·Yasushi YoshikawaYoshiki Sawa
Jan 13, 2019·The Journal of Thoracic and Cardiovascular Surgery·Bjørn BraathenTheis Tønnessen

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