PMID: 3966742Jan 1, 1985

Hemodynamic response to oxygen therapy in chronic obstructive pulmonary disease

Annals of Internal Medicine
R M TimmsG W Williams


At six centers, 203 patients with stabilized hypoxemic chronic obstructive pulmonary disease were evaluated hemodynamically during a continuous or 12-hour oxygen therapy program. Neither oxygen therapy program resulted in correction or near-correction of the baseline hemodynamic abnormalities. The continuous oxygen therapy group did show improvement in pulmonary vascular resistance, pulmonary arterial pressure, and stroke volume index. The improvement in pulmonary vascular resistance was associated with improved cardiac function, as evidenced by an increase in baseline and exercise stroke volume index. The nocturnal oxygen therapy group showed stable hemodynamic variables. For both groups, changes in mean pulmonary artery pressure during the first 6 months were associated with subsequent survival after adjustment for association with the baseline mean pulmonary artery pressure. Continuous oxygen therapy can improve the hemodynamic abnormalities of patients with hypoxic chronic obstructive pulmonary disease. The hemodynamic response to this treatment is predictive of survival.


Sep 9, 1999·Liver Transplantation and Surgery : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·J Y FindlayMichael J Krowka
Aug 5, 2011·Lung·Vadim FayngershJames R Klinger
Sep 1, 1989·Journal of the American College of Cardiology·S Rich, B H Brundage
Mar 1, 1995·The Journal of Thoracic and Cardiovascular Surgery·A CohenA Schachner
Sep 12, 2000·Lancet·T HigenbottamE Demoncheaux
Oct 10, 2001·Clinics in Chest Medicine·Alfred P Fishman
Feb 2, 2010·Archivos de bronconeumología·María Asunción Nieto Barbero
Jun 1, 1987·Journal of the American College of Cardiology·D A MorrisonM I Schwarz
Mar 19, 2002·Respirology : Official Journal of the Asian Pacific Society of Respirology·Wataru HidaKunio Shirato
Sep 14, 1995·The New England Journal of Medicine·S P Tarpy, Bartolomé R Celli
May 22, 2007·Antioxidants & Redox Signaling·Ioana R Preston
Dec 23, 2011·Current Opinion in Pulmonary Medicine·Randy OrrMichael J Cuttica
Oct 26, 2005·Archives of Disease in Childhood·D S UrquhartA Jaffé
Sep 14, 2012·Pulmonary Medicine·Adil ShujaatJames D Cury
Jul 9, 1998·American Journal of Respiratory and Critical Care Medicine·A AidaY Kawakami
May 15, 2007·American Journal of Respiratory and Critical Care Medicine·Gerard CrinerNational Emphysema Treatment Trial Research Group
May 6, 2008·Proceedings of the American Thoracic Society·Victor KimAmir Sharafkhaneh
Nov 30, 2007·International Journal of Chronic Obstructive Pulmonary Disease·Ferit AkgülIgor Pershukov
Sep 15, 2009·International Journal of Chronic Obstructive Pulmonary Disease·David Anderson, W MacNee
Dec 13, 2005·Treatments in Respiratory Medicine·Thomas J Ringbaek
Aug 29, 2014·BioMed Research International·Amirmasoud ZangiabadiDimitar Sajkov
Aug 23, 1985·Deutsche medizinische Wochenschrift
Nov 21, 2007·COPD·Adam L FriedlanderRussell P Bowler
Nov 26, 2013·Clinics in Chest Medicine·Maor SaulerTerence K Trow
Apr 8, 2009·Chest·Ari ChaouatSerge Adnot
Feb 1, 1990·Chest·J Butler
Apr 15, 2015·Thorax·Maxine HardingeBritish Thoracic Society Standards of Care Committee
Jan 1, 1994·Chest·A F BarkerA L Plummer
May 1, 1996·Chest·Emmanuel Weitzenblum
May 13, 2005·Chest·Emmanuel Weitzenblum, Ari Chaouat
May 3, 2012·Cardiology Clinics·Todd M Kolb, Paul M Hassoun
Mar 3, 2009·Progress in Cardiovascular Diseases·Dimitar Sajkov, R Doug McEvoy
Jan 28, 2009·La Presse médicale·Emmanuel WeitzenblumAri Chaouat
Mar 14, 2007·Mayo Clinic Proceedings·Jay H RyuMichael D McGoon
Jun 23, 2015·Respiratory Medicine·Jonathan R Weir-McCallJ Graeme Houston
Oct 11, 1991·Journal of Cardiothoracic and Vascular Anesthesia·J E Calvin
Jul 1, 1986·The Journal of Pediatrics·W BermanL A Papile
Feb 1, 1994·Chest·C B Cooper
Dec 13, 2005·European Journal of Pharmacology·Takaaki NakamotoKenji Sorimachi
Apr 17, 1999·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·X Leverve
Apr 18, 2016·Heart Failure Reviews·Michael J Cuttica
Jun 26, 2001·Respiratory Medicine·A J CrockettJ H Alpers
May 9, 2014·Current Opinion in Pharmacology·Mark A Giembycz, Donald H Maurice
May 10, 2005·Respiratory Medicine·Zhiwen ZhuRichard W Light
Nov 5, 1997·Clinics in Chest Medicine·H I Palevsky
Sep 1, 1986·Pediatric Pulmonology·J E MarcotteG J Canny
Oct 29, 2011·Pulmonary Circulation·Jason A StammMichael A Mathier
Nov 18, 2003·Clinical Physiology and Functional Imaging·Toru HiragaTakeshi Ogura
Apr 10, 2018·Current Opinion in Organ Transplantation·Rade Tomic, Marshall I Hertz
Oct 20, 2005·The Cochrane Database of Systematic Reviews·J M CranstonJ H Alpers
Dec 19, 2007·Circulation·MeiLan K HanFernando J Martinez
May 11, 2018·American Journal of Respiratory and Critical Care Medicine·Gabor KovacsHorst Olschewski
Nov 1, 1985·Thorax·T B Stretton
Aug 22, 2015·The European Respiratory Journal·Melanie J BrewisAndrew J Peacock
Jun 30, 2017·European Respiratory Review : an Official Journal of the European Respiratory Society·Maria Rosa GhignaKatrien Grünberg
Dec 14, 2018·The European Respiratory Journal·Steven D NathanWerner Seeger
Apr 20, 2007·The Cochrane Database of Systematic Reviews·M L NonoyamaR S Goldstein
Dec 14, 2012·Expert Review of Respiratory Medicine·Surinder K Jindal, Ritesh Agarwal
Jan 25, 2020·British Journal of Pharmacology·Marija GredicNorbert Weissmann
Dec 13, 2017·Current Opinion in Pulmonary Medicine·Vivek N Iyer
Dec 20, 2017·Current Opinion in Pulmonary Medicine·Kshitij ChatterjeeShoaib Alam
Apr 9, 2020·Journal of Clinical Sleep Medicine : JCSM : Official Publication of the American Academy of Sleep Medicine·Bilal SamhouriNeal F Chaisson
Sep 30, 2020·Journal of Clinical Medicine·Kazuto MatsunagaTsunahiko Hirano
Nov 1, 1993·The American Review of Respiratory Disease·C G Salvaterra, L J Rubin
Oct 23, 2019·European Respiratory Review : an Official Journal of the European Respiratory Society·Davide EliaSergio Harari
Jun 1, 1993·The American Review of Respiratory Disease·F SérièsJ La Forge
Nov 6, 2003·JAMA : the Journal of the American Medical Association·Don D SinNick R Anthonisen
Aug 7, 2019·Medicina·Steven J Cassady, Robert M Reed
Sep 29, 2020·ERJ Open Research·Marlies van DijkMarieke L Duiverman
Aug 5, 2020·The European Respiratory Journal·Yochai AdirAri Chaouat
Dec 1, 2020·Respiratory Physiology & Neurobiology·Shrilaxmi Bagali, Kusal K Das
Feb 13, 2021·Journal of Clinical Medicine·Marta Marin-OtoJuan P De-Torres

Related Concepts

Diastolic Blood Pressure
Cardiopulmonary Exercise Test
Cardiac Catheterization Procedures
Lung Diseases, Obstructive
Oxygen Therapy Care
Stroke Volume
Pulmonary Vascular Resistance

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Systemic Juvenile Idiopathic Arthritis

Systemic juvenile idiopathic arthritis is a rare rheumatic disease that affects children. Symptoms include joint pain, but also fevers and skin rashes. Here is the latest on this disease.

Chromatin Regulation and Circadian Clocks

The circadian clock plays an important role in regulating transcriptional dynamics through changes in chromatin folding and remodelling. Discover the latest research on Chromatin Regulation and Circadian Clocks here.

Central Pontine Myelinolysis

Central Pontine Myelinolysis is a neurologic disorder caused most frequently by rapid correction of hyponatremia and is characterized by demyelination that affects the central portion of the base of the pons. Here is the latest research on this disease.

Myocardial Stunning

Myocardial stunning is a mechanical dysfunction that persists after reperfusion of previously ischemic tissue in the absence of irreversible damage including myocardial necrosis. Here is the latest research.

Pontocerebellar Hypoplasia

Pontocerebellar hypoplasias are a group of neurodegenerative autosomal recessive disorders with prenatal onset, atrophy or hypoplasia of the cerebellum, hypoplasia of the ventral pons, microcephaly, variable neocortical atrophy and severe mental and motor impairments. Here is the latest research on pontocerebellar hypoplasia.

Cell Atlas Along the Gut-Brain Axis

Profiling cells along the gut-brain axis at the single cell level will provide unique information for each cell type, a three-dimensional map of how cell types work together to form tissues, and insights into how changes in the map underlie health and disease of the GI system and its crosstalk with the brain. Disocver the latest research on single cell analysis of the gut-brain axis here.

Chronic Traumatic Encephalopathy

Chronic Traumatic Encephalopathy (CTE) is a progressive degenerative disease that occurs in individuals that suffer repetitive brain trauma. Discover the latest research on traumatic encephalopathy here.