Hemodynamic stability during biventricular pacing after cardiopulmonary bypass.

Journal of Cardiothoracic and Vascular Anesthesia
Mathew E SpotnitzHenry M Spotnitz

Abstract

To assess the stability of cardiac output, mean arterial pressure, and systemic vascular resistance during biventricular pacing (BiVP) optimization. Substudy analysis of data collected as part of a randomized controlled study examining the effects of optimized temporary BiVP after cardiopulmonary bypass (CPB). A single-center study at a university-affiliated tertiary care hospital. Cardiac surgery patients at risk of left ventricular failure after CPB. BiVP was optimized immediately after CPB. Atrioventricular delay (7 unique settings) was optimized first, followed by the left ventricular pacing site (3 unique settings) and then the interventricular delay (9 unique settings). Each setting was tested twice for 10 seconds each time. Vasoactive medication and fluid infusion rates were held constant. Aortic flow velocity and radial artery pressure were digitized, recorded, and averaged over single respiratory cycles. Least squares and linear regression/Wilcoxon analyses were applied to the first 7 patients studied. Subsequently, curvilinear analysis was applied to 15 patients. Changes in mean arterial pressure and systemic vascular resistance were statistically insignificant or too small to be meaningful by least squares analysis. ...Continue Reading

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Citations

Oct 24, 2012·Journal of Cardiothoracic Surgery·Jose B García-BengocheaJosé R González Juanatey
Jul 23, 2013·The Annals of Thoracic Surgery·Henry M SpotnitzCraig R Smith
Jul 31, 2012·The Journal of Thoracic and Cardiovascular Surgery·Huy V NguyenHenry M Spotnitz
Oct 7, 2011·Pacing and Clinical Electrophysiology : PACE·Daniel Y Wang, Henry M Spotnitz
Jan 25, 2013·American Journal of Therapeutics·Jason Han Chua, Rudolph Nguyen

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