Hemodynamic stress distribution reflects ischemic clinical symptoms of patients with moyamoya disease

Clinical Neurology and Neurosurgery
Satoshi TakahashiBan Mihara

Abstract

Currently, the probability of diagnosing asymptomatic moyamoya disease is increasing. In this study, we consider a less invasive method for predicting future ischemic symptoms in patients with moyamoya disease. We reviewed cerebral blood flow (CBF)-related data obtained by xenon CT imaging (XeCT) in six patients with ischemic-type or asymptomatic moyamoya disease. The data were obtained as volume data using a 320-row CT, and applied to the automated region-of-interest-determining software (3DSRT) and converted to standardized images. Eight CBF-related parameters, including CBF value, cerebrovascular reserve capacity (CVRC), and hemodynamic distribution (hdSD), were compared between asymptomatic hemispheres and ischemic symptomatic hemispheres. A significant difference was determined by a two-sample t test. A difference with p<0.05 was considered significant. When statistically significant differences between parameters of asymptomatic hemispheres and ischemic symptomatic hemispheres were identified, cut-off points were calculated with receiver operating characteristic (ROC) curves. Change in the parameters before and after bypass surgery was also assessed. Of the eight CBF-related parameters evaluated, statistically significant...Continue Reading

References

Jan 1, 1983·Stroke; a Journal of Cerebral Circulation·J Suzuki, N Kodama
Oct 24, 2006·Radiation Medicine·Ryo TakeuchiKaname Matsumura
Oct 23, 2008·Lancet Neurology·Satoshi Kuroda, Kiyohiro Houkin
Apr 2, 2009·Neurosurgical Focus·Gordon M BurkeBernard R Bendok
Nov 26, 2009·Journal of Neurotrauma·Gerrit Alexander SchubertClaudius Thomé
Nov 7, 2013·Stroke; a Journal of Cerebral Circulation·Gerrit Alexander SchubertClaudius Thomé
Jan 7, 2014·Heart & Lung : the Journal of Critical Care·S ZimmermannV Mahler
Mar 29, 2014·Stroke; a Journal of Cerebral Circulation·Susumu MiyamotoUNKNOWN JAM Trial Investigators
Jan 7, 2015·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Satoshi TakahashiBan Mihara
Mar 6, 2015·Neurologia Medico-chirurgica·Satoshi Kuroda, UNKNOWN AMORE Study Group
Mar 31, 2015·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Satoshi TakahashiBan Mihara

❮ Previous
Next ❯

Related Concepts

Related Feeds

Brain Ischemia

Brain ischemia is a condition in which there is insufficient blood flow to the brain to meet metabolic demand. Discover the latest research on brain ischemia here.

Related Papers

Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association
Satoshi TakahashiBan Mihara
Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association
Satoshi TakahashiBan Mihara
Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine
Hidehiko OkazawaMasaaki Takahashi
© 2021 Meta ULC. All rights reserved