Hemodynamics in the immediate post-transplantation period in alcoholic and viral cirrhosis.

World Journal of Gastroenterology : WJG
Waleed K Al-HamoudiSamuel S Lee

Abstract

To study the hemodynamics in the immediate post transplant period and compare patients with alcoholic vs viral cirrhosis. Between 2000-2003, 38 patients were transplanted for alcoholic cirrhosis and 28 for postviral cirrhosis. Heart rate (HR), central venous pressure (CVP), mean arterial pressure (MAP), pulmonary capillary wedge pressure (PCWP), cardiac index (CI), systemic vascular resistance index (SVRI), pulmonary artery pressure (PAP), and pulmonary vascular resistance index (PVRI) were measured immediately and 24 h post transplantation. Hyperdynamic circulation persisted at 24 h following transplantation with an elevated CI of 5.4 +/- 1.3 L/(min x m(2)) and 4.9 +/- 1.0 L/(min x m(2)) in the viral and alcoholic groups, respectively, and was associated with a decreased SVRI. Within the first 24 h, there was a significant decrease in HR and increase in MAP; the extent of the change was similar in both groups. The CVP, PCWP, and SVRI increased, and CI decreased in the viral patients, but not the alcoholic patients. Alcoholics showed a lower PVRI (119 +/- 52 dynes/(cm(5) x m(2)) vs 166 +/- 110 dynes/(cm(5) x m(2)), P < 0.05) and PAP (20 +/- 7 mmHg vs 24 +/- 7 mmHg, P < 0.05) compared to the viral group at 24 h. Hyperdynamic cir...Continue Reading

References

Feb 1, 1992·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·J M HendersonM H Kutner
Mar 1, 1990·Journal of Hepatology·A G AgustíR Rodriguez-Roisin
Feb 1, 1989·The American Review of Respiratory Disease·A G AgustiJ Bosch
Dec 13, 1986·British Medical Journal·G DecauxF Delwiche
Dec 1, 1986·Drug and Alcohol Dependence·R H JohnsonD G Lambie
Dec 1, 1985·British Journal of Clinical Pharmacology·L G Howes, J L Reid
Nov 15, 1980·Lancet·G DuncanE A Whiteside
Aug 1, 1995·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·A GadanoF Durand
Jul 15, 1995·Annals of Internal Medicine·A MatsumotoM Omata
Nov 1, 1994·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·R J Groszmann
Nov 1, 1993·Journal of Hepatology·M T Hendrickse, D R Triger
Feb 1, 1993·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·A HadengueS Erlinger
Mar 1, 1993·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·M NavasaJ Rodés
Aug 1, 1996·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Z Ma, S S Lee
Nov 1, 1996·Scandinavian Journal of Gastroenterology·S LindgrenG Sundkvist
Aug 29, 1998·Journal of Hepatology·J H HenriksenN J Christensen
Jul 29, 2000·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·R P Myers, S S Lee
Jan 12, 2002·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Daisheng SongSamuel S Lee
Nov 24, 2004·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·George TherapondosPeter C Hayes
Jun 17, 2008·Transplantation Proceedings·G Della RoccaP Chiarandini
Sep 18, 2008·Liver International : Official Journal of the International Association for the Study of the Liver·Lien Van LandeghemFrederik Nevens
Mar 20, 2009·Transplantation·Tamer R FouadSamuel S Lee
Mar 28, 2009·Liver International : Official Journal of the International Association for the Study of the Liver·James Frith, Julia L Newton

❮ Previous
Next ❯

Citations

Jan 11, 2013·Journal of Aging Research·Alan J PearceMeg E Morris
Jan 22, 2011·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Hongqun Liu, Samuel S Lee
Jan 8, 2019·Clinical Cardiology·Wilson C KwanDavid R Laughrun
Apr 6, 2012·BMC Public Health·Jessica Y Andrews, Stuart A Kinner

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Seminars in Liver Disease
Saleh A AlqahtaniS S Lee
Hepatology : Official Journal of the American Association for the Study of Liver Diseases
Marc MejiasMercedes Fernández
Hepatology : Official Journal of the American Association for the Study of Liver Diseases
Martin HennenbergJörg Heller
Pharmacological Research : the Official Journal of the Italian Pharmacological Society
Sándor Bátkai, Pál Pacher
© 2021 Meta ULC. All rights reserved