Hemofiltration during cardiopulmonary bypass does not decrease the incidence of atrial fibrillation after cardiac surgery

Anesthesia and Analgesia
William J MauermannWilliam C Oliver

Abstract

Atrial fibrillation (AF) occurs in 20%-50% of patients after cardiac surgery and is associated with increased morbidity and mortality. Corticosteroids are reported to decrease the incidence of postoperative AF, presumably by attenuating inflammation caused by surgery and cardiopulmonary bypass (CPB). We hypothesized that hemofiltration during CPB, which may attenuate inflammation, might decrease the incidence of AF after cardiac surgery. This was a retrospective review of patients previously enrolled in a double-blind, placebo-controlled trial evaluating the effects of perioperative steroid therapy and hemofiltration during CPB on duration of postoperative mechanical ventilation. In that study, 192 patients undergoing cardiac surgery were randomized to 1 of 3 groups: controls (placebo), hemofiltration during CPB, or perioperative steroid therapy. Patient records were reviewed to determine the incidence of new onset AF defined as any electrocardiogram evidence of AF or AF diagnosed by the patients' clinicians. Of the 192 enrolled patients, 3 were excluded for protocol violations and 4 were excluded for history of chronic AF. Data from 185 patients from the original study were available for review. Sixty patients (32%) had new on...Continue Reading

References

Dec 1, 1993·The Annals of Thoracic Surgery·A B MillarC Lincoln
Dec 1, 1993·The Annals of Thoracic Surgery·S AndreassonB Risberg
Sep 1, 1993·The Annals of Thoracic Surgery·L L CreswellJ L Cox
Sep 3, 2002·Journal of the American College of Cardiology·Elizabeth M MahoneyWilliam S Weintraub
Feb 1, 2003·Scandinavian Journal of Surgery : SJS : Official Organ for the Finnish Surgical Society and the Scandinavian Surgical Society·T HakalaM Hippeläinen
May 23, 2003·Anesthesia and Analgesia·Per HalvorsenTerje Veel
Mar 19, 2004·Journal of the American College of Cardiology·Jonathan S Steinberg
Apr 6, 2004·The Annals of Thoracic Surgery·Jarmo LahtinenTatu Juvonen
Apr 15, 2004·JAMA : the Journal of the American Medical Association·Joseph P MathewUNKNOWN Multicenter Study of Perioperative Ischemia Research Group
Jul 7, 2005·The Journal of Thoracic and Cardiovascular Surgery·Kriengchai PrasongsukarnSamuel V Lichtenstein
Jan 28, 2006·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Keiichi IshidaMasaru Miyazaki
Feb 7, 2006·Journal of Cardiothoracic and Vascular Anesthesia·Gudrun LammBernd Eber
Apr 12, 2007·JAMA : the Journal of the American Medical Association·Jari HalonenTapio Hakala
Aug 25, 2009·The Journal of Thoracic and Cardiovascular Surgery·Oliver J LiakopoulosThorsten Wahlers

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Citations

Feb 22, 2012·ISRN Cardiology·C ChelazziA R De Gaudio
May 4, 2010·The Journal of Thoracic and Cardiovascular Surgery·Jeanne ShenRichard B Schuessler
Jan 9, 2015·Annals of Cardiac Anaesthesia·David W BarbaraWilliam J Mauermann
Dec 2, 2010·European Journal of Anaesthesiology·Hans P SviggumKent H Rehfeldt
Mar 27, 2012·Medicina intensiva·J L Pérez VelaUNKNOWN Grupo de Trabajo de Cuidados Intensivos Cardiológicos y RCP de SEMICYUC, con el aval científico de la SEMICYUC

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