PMID: 6403733Jan 1, 1983Paper

Hemoglobin A1C in home parenteral nutrition

JPEN. Journal of Parenteral and Enteral Nutrition
J M Mirtallo, P J Fabri

Abstract

Hemoglobin A1C or glycosylated hemoglobin has been described as being effective in monitoring long-term glucose control in diabetics. The usefulness of HbA1C in reflecting glucose homeostasis during chronic hypertonic dextrose infusions in 6 patients receiving cyclic home TPN was studied at monthly intervals. Grouped data for the 34 values representing study periods of 5 to 10 months averaged 7.5 +/- 0.2% (Mean +/- SEM) indicating that HbA1C levels were not elevated above normal (4-8%) in these patients while receiving a dextrose based diet. Final values of HbA1C (7.3 +/- 0.4%, mean +/- SEM) although lower than early values (8.7 +/- 0.6%, mean +/- SEM) were not significantly different (p greater than 0.05, Student's paired t-test). The change in HbA1C that occurred in these patients probably reflects the response to an altered glucose load infused by the patient. HbA1C is a convenient and apparently accurate method of evaluating chronic glucose tolerance in patients receiving home TPN and may be used as an alternate method for monitoring glucose tolerance on an outpatient basis.

References

Sep 1, 1979·Annals of Internal Medicine·P J DunnR E Gleason
Mar 2, 1979·JAMA : the Journal of the American Medical Association·A Lev-Ran, W P VanderLaan
Aug 19, 1976·The New England Journal of Medicine·R J KoenigA Cerami
Jul 1, 1981·Annals of Internal Medicine·A L Kennedy, T J Merimee
Mar 1, 1980·Annals of Internal Medicine·G BodenO E Owen

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Citations

Sep 5, 1992·Lancet·C MatuchanskyJ P Allard
Mar 1, 1985·The Australian and New Zealand Journal of Psychiatry·P N GilchristJ Hoogendorp
Jul 1, 1987·Drug Intelligence & Clinical Pharmacy·J M Mirtallo, T Oh

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