Hemoglobin as a possible biochemical index of hypertension-induced vascular damage

Journal of Physiological Anthropology
Yuji ShimizuTakahiro Maeda

Abstract

We previously reported on the positive association of hemoglobin with hypertension and atherosclerosis. On the other hand, hepatocyte growth factor (HGF) has been evaluated as a possible biochemical index of hypertension-induced vascular damage. However, no studies have reported on a correlation between hemoglobin and HGF accounting for hypertension status. A cross-sectional study of 1108 subjects (392 men and 716 women, 40-93 years old) who were undergoing a general checkup in 2014 was conducted. Multiple linear regression analysis adjustment for known cardiovascular risk factors showed no significant correlation between hemoglobin and HGF in non-hypertensive subjects, but a significant positive correlation in hypertensive subjects; β (parameter estimate) = 0.3 (p = 0.975) for non-hypertensive men, β = 0.4 (p = 0.925) for non-hypertensive women, β = 32.7 (p < 0.001) for hypertensive men, and β = 18.7 (p = 0.002) for hypertensive women. We found a significant positive correlation between hemoglobin and HGF among hypertensive men and women. Like HGF, hemoglobin may be a useful indicator to evaluate hypertension-induced vascular damage. Since hemoglobin can easily be measured, these results support hemoglobin as an efficient tool...Continue Reading

References

Oct 13, 1995·Biochemical and Biophysical Research Communications·Y NakamuraK Matsumoto
May 1, 1994·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·H SakaguchiK Kobayashi
Jan 24, 1998·Biochemical and Biophysical Research Communications·S NakamuraT Ogihara
Jul 15, 1999·The Journal of Clinical Endocrinology and Metabolism·M NishimuraM Yoshimura
Oct 9, 1999·Hypertension Research : Official Journal of the Japanese Society of Hypertension·R MorishitaT Ogihara
Dec 29, 2000·Hypertension Research : Official Journal of the Japanese Society of Hypertension·M NishimuraM Yoshimura
Nov 28, 2002·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Yoshihito HayashiKazuaki Shimamoto
Oct 18, 2003·Journal of Atherosclerosis and Thrombosis·Ryuichi KawamotoYaemi Takagi
Oct 24, 2003·Nature·L M CalviD T Scadden
Nov 20, 2003·The Journal of Biological Chemistry·Xue WangAugustine M K Choi
Jul 31, 2004·Journal of the American Society of Nephrology : JASN·Dierk H Endemann, Ernesto L Schiffrin
Apr 12, 2006·The Journal of Experimental Medicine·Yoshihiro Yamada, Nobuyuki Takakura
Jun 22, 2006·Atherosclerosis·Evelyn TorsneyQingbo Xu
Nov 2, 2006·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Karin DaubMeinrad Gawaz
Apr 10, 2010·Arteriosclerosis, Thrombosis, and Vascular Biology·Emoke NagyJózsef Balla
Oct 18, 2014·Frontiers in Physiology·Viktória JeneyJózsef Balla

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Citations

Oct 6, 2016·Aging·Yuji ShimizuTakahiro Maeda
May 5, 2018·Environmental Health and Preventive Medicine·Yuji ShimizuTakahiro Maeda
Jun 6, 2017·Geriatrics & Gerontology International·Yuji ShimizuTakahiro Maeda
May 3, 2019·Environmental Health and Preventive Medicine·Yuji ShimizuTakahiro Maeda
Feb 8, 2021·Environmental Health and Preventive Medicine·Yuji Shimizu, Takahiro Maeda

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