PMID: 1200978Dec 1, 1975Paper

Hemoglobin synthesis studies of a family with alpha-thalassemia trait and sickle cell trait

Biochemical Genetics
J R ShaefferL J Kleve

Abstract

The ratio of total globin alpha to beta chain synthesis was determined in reticulocytes isolated from the blood of the members of a black family, some of whom had sickle cell trait with low blood HbS concentrations (25-30%). The results support the hypothesis that sickle cell trait individuals with low HbS concentrations also carry a gene for alpha-thalassemia.

References

Dec 6, 1972·Nature: New Biology·J B Clegg, D J Weatherall
Mar 15, 1974·Biochemical and Biophysical Research Communications·J DeSimoneJ Shaeffer
Jul 24, 1974·Biochemical and Biophysical Research Communications·J DeSimoneJ Shaeffer
Feb 1, 1972·The Journal of Clinical Investigation·E Schwartz, J Atwater
Dec 1, 1968·Clinica Chimica Acta; International Journal of Clinical Chemistry·R N WrightstoneA van der Sar
Sep 1, 1960·Clinica Chimica Acta; International Journal of Clinical Chemistry·T H HUISMAN
Oct 7, 1964·Annals of the New York Academy of Sciences·D J WEATHERALL
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Oct 1, 1951·The Journal of Clinical Investigation·J V NEELH A ITANO

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Citations

Jan 1, 1982·Human Genetics·G Martínez, M E Cañizares
Jan 1, 1983·Transactions of the Royal Society of Tropical Medicine and Hygiene·P W van Dongen, M A van't Hof
Oct 1, 1979·The Journal of Clinical Investigation·K K MatthayD F Bainton
Nov 16, 2005·Archives of Neurology·Michael M Dowling

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