PMID: 9423222Jan 10, 1998Paper

Hemolytic uremic syndrome following taipan envenomation with response to plasmapheresis

Pathology
R G CobcroftP Masci

Abstract

We report a case of hemolytic uremic syndrome (HUS) in a 33 year old male who was bitten by a taipan, with apparent massive envenomation. The microangiopathic hemolytic anemia (MAHA) and thrombocytopenic aspects of his HUS appeared to respond to plasmapheresis, but his anuric renal failure persisted. He also had prolonged severe muscular paralysis which gradually began to resolve over the course of two weeks. At this point he suffered a cardiac arrest sustaining severe and subsequently fatal hypoxic brain injury. This case raises the possibility that the taipan venom may have induced HUS by damaging the renal endothelium. His cardiac arrest was not apparently related to his HUS.

References

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Citations

Sep 25, 2008·Nature Clinical Practice. Nephrology·Visith Sitprija
Oct 4, 2006·Nephrology·Visith Sitprija
Feb 23, 2012·Seminars in Dialysis·Robert Clark SchuttMitchell H Rosner
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Sep 27, 2013·Cell Biochemistry and Biophysics·Junzhang ChengRong Chen
Jun 21, 2019·Clinical Toxicology : the Official Journal of the American Academy of Clinical Toxicology and European Association of Poisons Centres and Clinical Toxicologists·Tzvi-Ran Ilan RahmaniOri Galante
Apr 28, 2019·Journal of Thrombosis and Thrombolysis·Ganesh MohanDhivya Kandasamy
Aug 5, 2021·SAGE Open Medical Case Reports·Selladurai PirasathDilani Gajan

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