Hemopericardium and Cardiac Tamponade in a Patient Treated with Dabigatran Etexilate

Korean Circulation Journal
Filiz KızılırmakHabibe Gamze Canpolat

Abstract

Dabigatran etexilate is one of the new oral anticoagulants approved to reduce the risk of stroke in patients with atrial fibrillation (AF). A variety of bleeding complications with dabigatran have been reported, but reports of hemopericardium are rare. We described a case of a 66 year-old female patient with non-valvular AF receiving dabigatran etexilate 150 mg twice daily for one year who suffered from hemopericardium. Her laboratory tests performed 1 year prior were normal and her admission tests revealed acute renal failure and elevated international normalized ratio (INR) level (4.79). Urgent pericardiocentesis was followed by improved renal functions and normalized INR. Dabigatran etexilate is a new oral anticoagulant that is increasingly used in daily practice. However, life-threatening complications warrant caution. Elevated INR may be related with overdose but the association of bleeding risk of dabigatran and INR requires further confirmation.

References

Sep 1, 2009·The New England Journal of Medicine·Stuart J ConnollyUNKNOWN RE-LY Steering Committee and Investigators
Nov 26, 2010·Thrombosis and Haemostasis·Tomas L LindahlUNKNOWN Expert Group on Coagulation of the External Quality Assurance in Laboratory Medicine in Sweden
Apr 11, 2012·Pharmacotherapy·Cassie A BartonRay E Keller
Jul 13, 2012·The Annals of Pharmacotherapy·Eliza A Dy, Dane L Shiltz
Jul 18, 2012·Clinical Toxicology : the Official Journal of the American Academy of Clinical Toxicology and European Association of Poisons Centres and Clinical Toxicologists·Leah KernanKeith Boesen
Dec 12, 2012·The American Journal of the Medical Sciences·Yasir Lal, Joel Van Heukelom

❮ Previous
Next ❯

Citations

May 20, 2020·Arquivos brasileiros de cardiologia·Adem AdarFahri Cakan
Dec 21, 2017·Texas Heart Institute Journal·Qurat-Ul-Ain JelaniAdam Schussheim

❮ Previous
Next ❯

Related Concepts

Related Feeds

Atrial Filbrillation

Atrial fibrillation refers to the abnormal heart rhythm characterized by rapid and irregular beating of the atria. Here is the latest research.

Atrial Fibrillation

Atrial fibrillation is a common arrhythmia that is associated with substantial morbidity and mortality, particularly due to stroke and thromboembolism. Here is the latest research.

Arrhythmia

Arrhythmias are abnormalities in heart rhythms, which can be either too fast or too slow. They can result from abnormalities of the initiation of an impulse or impulse conduction or a combination of both. Here is the latest research on arrhythmias.

Related Papers

Clinical Therapeutics
Rangadham Nagarakanti, Christopher R Ellis
Zhonghua xin xue guan bing za zhi
Working Group on Thrombosis of Chinese Journal of Cardiology
South Dakota Medicine : the Journal of the South Dakota State Medical Association
William Hayes
© 2022 Meta ULC. All rights reserved