Hemophagocytic histiocytic sarcoma in a Japanese black cow

Veterinary Pathology
K MatsudaH Taniyama

Abstract

At necropsy, an 11-year-old Japanese Black cow with anemia, leukocytopenia, and progressive hind limb ataxia had marked diffuse splenomegaly and multiple masses in the thoracic vertebrae. Histologically, neoplastic erythrophagocytic histiocytes were in the splenic red pulp, vertebral masses, and blood vessels of the liver and lungs. The spinal cord was compressed by the vertebral masses. Clinicopathological, macroscopic, and histologic findings were consistent with hemophagocytic histiocytic sarcoma. Vertebral involvement with spinal cord compression and resultant hind limb ataxia is an unusual presentation for this tumor, which has been described mainly in dogs and cats.

References

Jul 1, 1987·Journal of Comparative Pathology·R H Sutton, M W McLennan
Mar 4, 2000·The American Journal of Dermatopathology·V K Affolter, P F Moore
Feb 24, 2001·The Journal of Veterinary Medical Science·T AnjikiK Kadota
Jul 10, 2002·Veterinary Pathology·V K Affolter, P F Moore
Sep 3, 2008·Veterinary Clinical Pathology·Julie WebbFrederic Almy

❮ Previous
Next ❯

Citations

Sep 29, 2012·Veterinary Clinical Pathology·Anne M BargerAmy L MacNeill
Aug 6, 2013·Veterinary Clinical Pathology·Mary LeissingerStephen Gaunt
Jul 29, 2016·Journal of Zoo and Wildlife Medicine : Official Publication of the American Association of Zoo Veterinarians·Luciana Fachini da CostaRenato Lima Santos
Mar 12, 2016·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·Atigan ThongtharbHiroyuki Nakayama
Mar 27, 2013·Veterinary Pathology·F Romero-PalomoJ C Gómez-Villamandos
Apr 12, 2018·Journal of the American Veterinary Medical Association·W Shane Sills, Elizabeth W Howerth
May 16, 2018·The Journal of Small Animal Practice·C IariaA Cascio
Jan 27, 2021·Journal of Comparative Pathology·Sirintra SirivisootTanit Kasantikul

❮ Previous
Next ❯

Related Concepts

Related Feeds

Anemia

Anemia develops when your blood lacks enough healthy red blood cells. Anemia of inflammation (AI, also called anemia of chronic disease) is a common, typically normocytic, normochromic anemia that is caused by an underlying inflammatory disease. Here is the latest research on anemia.