Hemophagocytic syndrome and T-cell lymphoma after kidney transplantation: a case report

Transplant International : Official Journal of the European Society for Organ Transplantation
P PeetersD Verbeelen

Abstract

Lymphoma in immunocompromised transplant patients is a feared cause of morbidity and mortality. Superimposed on the lymphoma and the transplantation immunosuppression is a rare condition: hemophagocytic syndrome (HS). HS is characterized by fever, hepatosplenomegaly and lymphadenopathy, skin rashes, jaundice, coagulopathy, and phagocytosis of blood elements with pancytopenia. Here we describe a rare but fatal case of a kidney transplant patient who developed T-cell lymphoma and HS, without evidence of EBV replication. A short review of the diagnosis, treatment, and prognosis of HS is given.

Citations

Apr 12, 2003·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Kalil MasriRandall C Starling
Jan 27, 2004·Transplantation·Alexandre KarrasUNKNOWN Groupe Coopératif de transplantation d'Ile de France
Oct 5, 2010·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·David S KotlyarGary R Lichtenstein
Apr 6, 2016·Journal of Nephropathology·Haydarali EsmailiMohammadali Mohajel-Shoja
Apr 22, 2016·International Urology and Nephrology·Edward J Filippone, John L Farber

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