Dec 1, 1988

Hemorheologic, micro- and macrocirculatory effects of hypervolemic hemodilution with middle molecular weight hydroxyethyl starch (Haes 200/0.62; 6 percent)

Infusionstherapie : offizielles Organ der Deutschen Arbeitsgemeinschaft für Künstliche Ernährung (DAKE) ; offizielles Organ der Österreichischen Arbeitsgemeinschaft für Klinische Ernähru (AKE) ; offizielles Organ der Deutschen Gesellschaft für Transfusion
F JungE Wenzel

Abstract

During a single blind study the influence of hypervolemic hemodilution (Infusion of 500 cc Elohäst 6%) on micro- and macrocirculation, transcutaneous pO2 and fluidity of blood of apparently healthy subjects was investigated. Blood pressure and heart rate remained unchanged during and after the infusion. One hour after the infusion there was a significant increase in the blood flow of the common carotid artery and the cutaneous circulation, and after 3 h a significant increase in conjunctival oxygen partial pressure was observed. The decrease in hematocrit was significant at all measuring points but most marked after 3 h (with 4.2 by volume). After 3 h and 6 h a significant increase in plasma viscosity and erythrocyte aggregation could be observed, whereas both parameters were unchanged during the early phase.

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Mentioned in this Paper

Blood Flow Velocity
Common Carotid Artery
HAES-steril
Erythrocyte Aggregation Measurement
Keoflo
Blood Flow
Entire Common Carotid Artery
Erythrocyte Aggregation Function
Partial Pressure of Oxygen
Hemodilution

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