PMID: 8957433Dec 1, 1996Paper

Hemorrhage and the use of blood products after adult cardiac operations: myths and realities

The Annals of Thoracic Surgery
S Bélisle, J F Hardy

Abstract

Several patient-, procedure-, and prescriber-related factors are thought to influence the decision to administer allogeneic blood products. We reexamine a number of assertions applied commonly to the practice of transfusion in cardiac operations. More than 50 original articles including a total of more than 10,000 patients from 70 centers were reviewed. Data from 5,426 patients operated on between 1990 and 1994 at the Montreal Heart Institute are presented. From our review of the literature, we conclude that postoperative mediastinal fluid drainage averages 917 mL and that aspirin therapy increases drainage by less than 300 mL in most studies, which should not increase use of blood products, insofar as a strict transfusional protocol is adhered to. Across centers, transfusions can vary eightfold for the same postoperative drainage. Data from our institution show that postoperative mediastinal drainage per se is not influenced by reoperation or by the type of operation. However, total blood losses and transfusion requirements remain increased in reoperative and complex procedures. Excessive mediastinal drainage resulting in increased transfusions occurs in 29% of patients. Exposure to allogeneic transfusions remains institution ...Continue Reading

References

Mar 1, 1988·The American Journal of Cardiology·V FusterJ H Chesebro
Jan 1, 1995·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·A ParolariP Biglioli
Apr 1, 1995·The Annals of Thoracic Surgery·J de HaanW van Oeveren
Jan 1, 1995·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·E OvrumG Tangen
Apr 1, 1995·Acta Anaesthesiologica Scandinavica·G EkbäckM Carlberg
Jan 1, 1996·Blood Coagulation & Fibrinolysis : an International Journal in Haemostasis and Thrombosis·H BevingT Ivert

❮ Previous
Next ❯

Citations

Sep 26, 1997·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·J F Hardy, S Bélisle
Jun 13, 2006·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·André VincentelliSylvain Bélisle
Jun 13, 2006·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Thomas Lecompte, Jean-François Hardy
Oct 15, 2008·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Helge MöllmannAlbrecht Elsässer
Sep 29, 2011·Journal of Anesthesia·Kazuyoshi ShimizuShunji Sano
Nov 26, 2010·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Alain VuylstekeMartin Utley
May 10, 2011·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Marie HacquardJean-Pierre Carteaux
May 24, 2011·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Alistair J ChapmanRobert L Hooker
Oct 29, 2002·The Annals of Thoracic Surgery·Bryan CollierLuis S Gonzalez
May 9, 2003·The Annals of Thoracic Surgery·Michel Durand, Olivier Chavanon
Oct 13, 1998·The Annals of Thoracic Surgery·G D WilliamsC Ramamoorthy
Sep 23, 2003·The Journal of Thoracic and Cardiovascular Surgery·Michael K BanburyDelos M Cosgrove
May 24, 2000·Thrombosis Research·P R BelcherR A Armstrong
Dec 9, 2003·International Journal of Cardiology·Ion S JovinGert Müller-Berghaus
Aug 4, 1999·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·M J Dalrymple-HayJ L Monro
Dec 21, 2011·The Journal of Laryngology and Otology·D C Sylvester, A P Coatesworth
Jun 20, 2002·Transfusion Medicine·J F BurmanJ R Pepper
Apr 12, 2007·Journal of Cardiothoracic Surgery·Juan J Jimenez RiveraMaria L Mora
Oct 5, 2014·Journal of Cardiothoracic and Vascular Anesthesia·Vidya K RaoPieter J van der Starre
Dec 3, 2008·The Journal of Experimental Medicine·Xueli YuanM Javeed Ansari
Jul 24, 2012·The Annals of Thoracic Surgery·Raffaele GiordanoCarlo Vosa
Dec 6, 2011·Current Problems in Surgery·Angela M Bader
Apr 1, 2008·Journal of Cardiothoracic and Vascular Anesthesia·Ambroise MontcriolFrançois Kerbaul
Aug 24, 1999·Applied Nursing Research : ANR·C R Curran
Jul 13, 2000·The Annals of Thoracic Surgery·E W MuriithiD J Wheatley
Dec 1, 1996·The Annals of Thoracic Surgery·G JanvierJ F Hardy
Dec 1, 1996·The Annals of Thoracic Surgery·J F HardyM Samama
Jul 26, 2005·The Annals of Thoracic Surgery·Christopher P CannonSary F Aranki
Jan 25, 2008·American Heart Journal·Paul S MylesUNKNOWN ATACAS Trial Group
Jan 11, 2000·The American Journal of Medicine·B F Mandell
Mar 4, 1998·The Annals of Thoracic Surgery·J S GammieC M Dyke
Jan 24, 2006·Journal of Cardiac Surgery·M DurandP Girardet
Apr 1, 2014·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Jinqian LiangXuhong Xue
Nov 10, 2010·Seminars in Cardiothoracic and Vascular Anesthesia·Tzong-Huei Chen, Robina Matyal

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2021 Meta ULC. All rights reserved