PMID: 18714742Aug 22, 2008Paper

Hemostasis abnormalities in liver cirrhosis: myth or reality?

Polskie Archiwum Medycyny Wewnętrznej
Armando Tripodi

Abstract

Chronic liver disease is characterized by a global hemostatic defect that includes platelet-vessel wall interaction (primary hemostasis), fibrinolysis and coagulation causing abnormalities of the relevant laboratory tests. The causal relationship between abnormal tests and bleeding has been widely accepted, despite the fact that abnormal tests are poorly associated with bleeding. Recent evidence from the literature disputes the above paradigm and open new directions for laboratory and clinical research in this field.

Related Concepts

Related Feeds

Blood Coagulation Signaling Pathways

Coagulation is the process by which a blood clot is formed. This process includes both the formation of a platelet plug as well as a cascade of clotting factors resulting in the formation of fibrin strands. Find the latest research on coagulation signaling pathways here.

Blood Clotting Disorders

Thrombophilia includes conditions with increased tendency for excessive blood clotting. Blood clotting occurs when the body has insufficient amounts of specialized proteins that make blood clot and stop bleeding. Here is the latest research on blood clotting disorders.

Related Papers

Seminars in Dialysis
Miriam GalbuseraPaola Boccardo
Acta Medica Croatica : C̆asopis Hravatske Akademije Medicinskih Znanosti
Eleonora GoluzaMladen Perić
Seminars in Dialysis
Dinkar Kaw, Deepak Malhotra
Seminars in Thrombosis and Hemostasis
Paola BoccardoMiriam Galbusera
© 2022 Meta ULC. All rights reserved