Hemostatic changes in patients with end stage renal disease undergoing hemodialysis

Clinica Chimica Acta; International Journal of Clinical Chemistry
Danyelle R A RiosLuci Maria Santana Dusse

Abstract

Patients undergoing hemodialysis may show both thrombotic complications and bleeding abnormalities. Hemostatic changes in patients on hemodialysis may result from alterations in vessel wall integrity and platelet function, and reduced blood flow in the native arteriovenous fistula. Vascular complications represent 20-25% of all hospitalizations of patients on hemodialysis. Literature survey revealed that changes in the hemostatic system may play a major role in vascular complications observed in these patients. Thus, it is essential to investigate hemostatic alterations in patients on hemodialysis so that adequate regimes for anticoagulant therapy could be implemented. In this review we discuss hemostatic abnormalities in end stage renal disease patients undergoing hemodialysis.

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Citations

Feb 3, 2012·Journal of Thrombosis and Thrombolysis·Danyelle R A RiosLuci M S Dusse
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Jul 3, 2013·Journal of Gastroenterology and Hepatology·Norifumi NumataKazuaki Chayama
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