Hendra Virus Infection in Horses: A Review on Emerging Mystery Paramyxovirus.

Journal of Equine Veterinary Science
Ameer KhusroMoises Cipriano-Salazar

Abstract

Hendra virus (HeV) is a zoonotic paramyxovirus which causes acute and deadly infection in horses (Equus caballus). It is a rare and unmanaged emerging viral infection in horses which is harbored by bats of the genus Pteropus (Australian flying foxes or fruit bats). The virus is pleomorphic in shape and its genome contains nonsegmented negative-stranded RNA with 18234 nucleotides in length. The virus is transmitted from flying foxes to horses, horse to horse, and horse to humans. Human-to-human transmission of HeV infection is not reported yet. The infection of HeV in horses is highly variable and shows broad range of signs and lesions including distinct respiratory and neurological disorders. Currently, there are no specific antiviral drugs available for the treatment of HeV infection in horses. Vaccination is considered as prime option to prevent HeV infection in horses. A subunit vaccine, called as "Equivac HeV vaccine" has been approved recently for preventing this viral infection in horses. In addition, a plethora of common preventive strategies could help restrict the inter- and intra-species transmission of HeV. Considering the scanty but severe fatality cases of this mystery virus as well as lack of proper attention by v...Continue Reading

Citations

Jan 23, 2021·Journal of Equine Veterinary Science·Ameer KhusroAlberto Barbabosa-Pliego
Aug 8, 2021·Animals : an Open Access Journal From MDPI·Alexandra Knox, Travis Beddoe
Sep 7, 2021·The Veterinary Journal·Nicola PusterlaEmir Hodzic

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