Henoch-Schönlein purpura with acute pancreatitis: analysis of 13 cases

BMC Pediatrics
Qin ZhangFang Deng

Abstract

Henoch-Schönlein purpura is a common small vessel vasculitis in children. Acute pancreatitis rarely presents as a complication of Henoch-Schönlein purpura and has not been well characterized. We retrospectively reviewed 13 cases of Henoch-Schönlein purpura with acute pancreatitis among 3212 patients who attended our hospital between January 2003 and June 2016 and analyzed their clinical characteristics, laboratory findings, imaging findings, treatment and overall prognosis. All patients had abdominal manifestations, including significant abdominal pain (13/13), vomiting (9/13), abdominal distension (3/13) and melena (6/13). Serum amylase level significantly increased in all patients, and urine amylase was increased in 7 cases (7/10). However, increased urine lapse was only noted in 2 cases (2/5), and diffuse swelling of the pancreas was seen in 2 cases (2/13) by abdominal ultrasonography. Although all patients had typical skin purpura (13/13), 5 patients (5/13) with acute pancreatitis initially experienced acute abdominal pain in clinical onset of Henoch-Schönlein purpura. Glucocorticoid therapy was effective in alleviating abdominal symptoms of Henoch-Schönlein purpura patients with acute pancreatitis. All patients were in goo...Continue Reading

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Citations

Aug 27, 2019·Pediatrics International : Official Journal of the Japan Pediatric Society·Hiroshi NinomiyaToshiyuki Fukao
Feb 9, 2019·Clinical Rheumatology·Şerife Gül KaradağNuray Aktay Ayaz
Aug 2, 2020·Pediatrics in Review·Avram H Derrow, Alison M Helfrich
Nov 30, 2018·Journal of Paediatrics and Child Health·Li WangYao Xu
Oct 13, 2020·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Pingping LiuYimin Zhu
Feb 5, 2019·Gastroenterology·Aliye Uc, Sohail Z Husain
Aug 8, 2021·Journal of Investigative Medicine : the Official Publication of the American Federation for Clinical Research·Li WangWanli Xue

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