PMID: 39465Sep 1, 1979

Heparin-induced changes in blood gas analysis (author's transl)

Der Anaesthesist
E GebertG Oepen


In modern blood gas analysis heparin is used for preventing coagulation in the syringe and the analyzer. If the amount of heparin added is too large the pH of the blood sample falls and so an artificial metabolic acidosis is induced. Consequently the amount of heparin used should be just enough to prevent blood coagulation without changing appreciably the acid-base status of the sample. High concentrations of inspired oxygen have no additional effect on the ability of heparin to alter the pH values.

Related Concepts

Carbonic Acid Ions
Analysis of Arterial Blood Gases and pH
Anion Gap
Mechanical Ventilation
Heparin, porcine
Oxygen Consumption
Carbon Dioxide
Blood Coagulation

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