Heparin-induced thrombocytopenia following pancreatectomy and islet auto-transplantation

Clinical Transplantation
Cristiana RastelliniLuca Cicalese

Abstract

We report the case of a female with chronic pancreatitis who underwent multiple surgical procedures leading to total resection of the pancreas with successful islet auto-transplantation. Postoperatively, she developed heparin-induced thrombocytopenia. Heparinization prior to islet infusion is currently recommended to prevent portal vein thrombosis. Antibodies against heparin are not standard pre-operative testing for islet transplantation. Timely screening for heparin-dependent anti-platelet antibody should be kept in consideration for elective surgical cases (especially following previous surgeries) including pancreatic islet allo- and auto-transplantation.

References

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Citations

Nov 10, 2013·Cell Medicine·Michihiro MaruyamaTakehide Asano
Jul 3, 2021·Journal of Clinical Medicine·Beata Jabłońska, Sławomir Mrowiec

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