Hepatic artery infusion and chemoembolization in the management of liver metastases

Cardiovascular and Interventional Radiology
S WallaceC Gianturco

Abstract

Hepatic metastases rather than the primary neoplasm usually dictate the course of the disease and patient's survival. For unresectable disease, intraarterial infusion of chemotherapy, embolization, and chemoembolization are viable alternatives. Intraarterial therapy for hepatic metastases is based on the dual blood supply of the normal liver (portal vein, 75%, and hepatic artery, 25%) and that of the tumors (hepatic artery, 90%). Intraarterial infusion delivers a higher concentration of chemotherapy, whereas chemoembolization adds ischemia and increased contact time with the tumor. Selective vascular occlusion for infusion, redistribution of the blood supply and pulsatile flow enhance the delivery of therapeutic agents to the liver.

References

Apr 1, 1979·Radiology·M GranmayehD Schwarten
Jan 1, 1979·European Surgical Research. Europäische Chirurgische Forschung. Recherches Chirurgicales Européennes·K F AronsenH Teder
Feb 1, 1990·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·G M MavligitS Wallace
Mar 1, 1989·Cardiovascular and Interventional Radiology·C KurodaT Kozuka
Mar 1, 1988·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·S A Rosenberg
Jun 1, 1988·AJR. American Journal of Roentgenology·J G LoriganS Wallace
Oct 1, 1988·AJR. American Journal of Roentgenology·F N O'KeeffeS Wallace
Aug 19, 1988·JAMA : the Journal of the American Medical Association·G M MavligitS Wallace
Dec 1, 1986·Current Problems in Cancer·C H CarrascoS Wallace
Jun 13, 1986·JAMA : the Journal of the American Medical Association·C H CarrascoG M Mavligit
May 15, 1986·Cancer·K C WrightC Gianturco
Oct 1, 1974·Cancer·L H EinhornJ A Gottlieb
Sep 1, 1972·The American Journal of Roentgenology, Radium Therapy, and Nuclear Medicine·S WallaceC Gianturco
Nov 1, 1971·Cancer·F J AnsfieldG W Wirtanen
Nov 1, 1984·Current Problems in Cancer·S WallaceC Gianturco
Jul 15, 1983·Cancer·S RajpalC P Karakousis
Aug 1, 1983·The American Journal of Medicine·Y Z PattG Mavligit
Oct 1, 1983·AJR. American Journal of Roentgenology·C H CarrascoS Wallace
Mar 15, 1984·Cancer·J E NiederhuberE Cozzi
Aug 1, 1982·Radiology·C CharnsangavejT Bowers
Aug 1, 1981·AJR. American Journal of Roentgenology·V P ChuangY Z Patt
Mar 1, 1983·AJR. American Journal of Roentgenology·C S SooH Carrasco
Oct 1, 1983·AJR. American Journal of Roentgenology·V P ChuangS Wallace
Jul 1, 1984·AJR. American Journal of Roentgenology·G LinA Lunderquist
Feb 1, 1982·AJR. American Journal of Roentgenology·V P ChuangT Bowers
May 1, 1981·Southern Medical Journal·A Y BedikianG P Bodey
Nov 1, 1981·Investigative Radiology·J H AndersonS Wallace
Mar 20, 1981·JAMA : the Journal of the American Medical Association·V P Chuang, S Wallace
Feb 13, 1964·The New England Journal of Medicine·R D SULLIVANE WATKINS

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Citations

Jan 1, 1995·Cardiovascular and Interventional Radiology·S E Macaulay, D M Coldwell
May 29, 2007·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Timothy M Pawlik, Michael A Choti
Feb 6, 2008·Cancer Imaging : the Official Publication of the International Cancer Imaging Society·J A Goode, M B Matson
Jun 24, 2003·AJR. American Journal of Roentgenology·Ichiro SakamotoNaofumi Matsunaga
Mar 26, 2014·Journal of Neuro-oncology·Shailendra JoshiRobert M Straubinger
Dec 6, 2014·Journal of Neuroanaesthesiology and Critical Care·Shailendra JoshiCharles W Emala
Nov 1, 2011·Cardiovascular and Interventional Radiology·Ricarda SeidenstickerJens Ricke
Apr 22, 2011·Expert Opinion on Drug Delivery·Oliver Dudeck, Jens Ricke
Sep 1, 1994·Journal of Vascular and Interventional Radiology : JVIR·E Carmody, K W Sniderman
May 1, 1991·Journal of Vascular and Interventional Radiology : JVIR·J D ElsonK O Ehrman
Jul 28, 2011·NMR in Biomedicine·Chang Hee LeeRichard C Semelka
Jun 20, 2015·Langenbeck's Archives of Surgery·Alexander MassmannChristof M Sommer
Jan 23, 2015·Der Radiologe·F Waneck
Dec 19, 2014·Der Radiologe·H Duan, M Hoffmann
Oct 1, 1995·Palliative Medicine·S N Jones
Oct 5, 2017·Cancer Control : Journal of the Moffitt Cancer Center·Bela KisKaren T Brown
Jun 15, 1993·Cancer·D J Vaughn, D G Haller
Mar 21, 1998·Journal of Magnetic Resonance Imaging : JMRI·R C SemelkaW G Cance
Feb 6, 2020·International Journal of Cancer. Journal International Du Cancer·Qi RuanXiaowen Liang
Mar 13, 2020·The Cochrane Database of Systematic Reviews·Mateusz J SwierzMalgorzata M Bala

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