Hepatic imaging following intra-arterial embolotherapy

Abdominal Radiology
Joseph Ralph KalliniRobert J Lewandowski

Abstract

To discuss guidelines and salient imaging findings of solid tumors treated with common intra-arterial procedures used in interventional oncology. A meticulous literature search of PubMed-indexed articles was conducted. Key words included "imaging + embolization," "imaging + TACE," "imaging + radioembolization," "imaging + Y90," "mRECIST," and "EASL." Representative post-treatment cross-sectional images were obtained from past cases in this institution. Intra-arterial therapy (IAT) in interventional oncology includes bland embolization, chemoembolization, and radioembolization. Solid tumors of the liver are the primary focus of these procedures. Cross-sectional CT and/or MR are the main modalities used to image tumors after treatment. Traditional size-based response criteria (WHO and RECIST) alone are of limited utility in determining response to IAT; tumoral necrosis and enhancement must be considered. Specifically for HCC, the EASL and mRECIST guidelines are becoming widely adopted response criteria to assess these factors. DWI, FDG-PET, and CEUS are modalities that play an adjunctive but controversial role. Radiologists must be aware that the different forms of intra-arterial therapy yield characteristic findings on cross-sec...Continue Reading

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Citations

Apr 4, 2016·Advances in Therapy·Joseph Ralph KalliniRobert J Lewandowski
Oct 27, 2017·AJR. American Journal of Roentgenology·Sahar SemaanBachir Taouli
Aug 16, 2017·European Journal of Nuclear Medicine and Molecular Imaging·Rehan AliRiad Salem
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Jan 31, 2020·Radiology. Imaging Cancer·Mishal Mendiratta-LalaMatthew S Davenport
Sep 25, 2021·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Frank H MillerRobert J Lewandowski

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