PMID: 16518276Mar 7, 2006Paper

Hepatic metastases from carcinomas of unknown primary site

Gastroentérologie Clinique Et Biologique
Damien PouesselMarc Ychou

Abstract

Hepatic metastases are often present at diagnosis of carcinoma of unknown primary site (CUP). The objective of this study was to describe the diagnostic and therapeutic strategies used. One hundred and eighteen patients were treated at the Cancer Center of Montpellier from 1993 to 2002 for CUP initially metastatic to the liver. Initial characteristics, diagnostic tests, chemotherapies and outcome were retrospectively recorded. The most frequent histological types observed were adenocarcinoma, undifferentiated, neuroendocrine and squamous-cell carcinomas. Hepatic metastases revealed the cancer in 66 patients and were isolated in 32 patients. Other metastatic sites involved lymph nodes, lung and bone. Pretreatment computed tomography scans of the chest, abdomen and pelvis evaluation were available for more than 80% of patients. Colonoscopy, gastroscopy and bronchoscopy were performed in 58, 56 and 26% of patients respectively. One hundred and seven patients had received at least a front-line of chemotherapy. Seventy-four patients had received platin salt-based chemotherapy, 67 in front-line treatment and 10 in second line. In first-line chemotherapy, overall response rates with or without platin were 19.4 and 20% respectively. On...Continue Reading

References

Feb 1, 1990·American Journal of Clinical Oncology·S A KambhuR Rosenbluth
Jan 1, 1981·Cancer·A B MillerA Winkler

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Citations

Sep 6, 2008·HPB : the Official Journal of the International Hepato Pancreato Biliary Association·E BucJ Belghiti
Nov 4, 2008·Clinical Oncology : a Journal of the Royal College of Radiologists·D TrivanovićD Stimac
Oct 8, 2011·European Journal of Radiology·Wieland H SommerKarin A Herrmann
Jul 14, 2010·The International Journal of Biochemistry & Cell Biology·Iris BarshackNitzan Rosenfeld
Jun 10, 2010·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Timothy D GilliganUNKNOWN American Society of Clinical Oncology
Jan 12, 2008·European Journal of Gastroenterology & Hepatology·Rune ErichsenHenrik T Sørensen
Jun 15, 2007·Acta Oncologica·Nicholas Pavlidis
Dec 11, 2013·Clinical Nuclear Medicine·Gaia GrassettoDomenico Rubello
Sep 21, 2020·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Hui QinHong Yang
Jan 31, 2021·Clinical & Experimental Metastasis·L MeijerC Loef

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