Hepatic nodular regenerative lesions in patients with hereditary haemorrhagic telangiectasia: computed tomography and magnetic resonance findings.

La Radiologia medica
A ScardapaneA A Stabile Ianora

Abstract

This study was done to evaluate the prevalence of regenerative hepatic nodules in patients with hereditary haemorrhagic telangiectasia (HHT). Between February 2001 and December 2010, 171 consecutive HHT patients (95 men and 76 women) were studied with triphasic multidetector computed tomography (MDCT) in 91 cases, magnetic resonance imaging (MRI) in 34 cases and both in the remaining 46 cases. The presence of diffuse vascular abnormalities and focal liver lesions were recorded. Hepatic arteriovenous malformations (HAVMs) were found in 126/171 (74%) patients. Arteriovenous shunts were found in 24/171 (14%) cases, arterioportal shunts in 52/171 (30%), mixed shunts in 26/171 (15%), telangiectases in 84/171 (49%) and transient hepatic attenuation differences (THADs) in 70/171 (41%). Hepatic nodular lesions were found in 6/171 (3.5%) patients (three men; three women). In 5/6 cases, vascular abnormalities were also evident. Two patients had a single lesion; four had multiple lesions. No lesion showed a central scar. Hyperenhancing hepatic regenerative lesions have a high prevalence in HHT patients, representing the response of liver parenchyma to hypoperfusion caused by HAVMs. These lesions are often multiple and may lead to nodular ...Continue Reading

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Citations

Mar 22, 2014·International Journal of Surgery Case Reports·Amato Antonio Stabile IanoraMarco Moschetta
Jul 6, 2016·The Journal of Laryngology and Otology·S Jervis, D Skinner
Feb 21, 2018·Abdominal Radiology·Valérie VilgrainPierre-Emmanuel Rautou
May 29, 2018·Virchows Archiv : an International Journal of Pathology·Christine SempouxPaulette Bioulac-Sage
Aug 28, 2018·Internal Medicine·Kazuhiko MoriiShiso Sato
May 12, 2020·Journal of Medical Ultrasonics·Hiroko NaganumaMasahiro Ogawa
Jan 3, 2020·The American Journal of Gastroenterology·Douglas A SimonettoPatrick S Kamath
Nov 26, 2020·Journal of Clinical Medicine·Joelle HarwinMichael A Ohliger

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