Hepatic tumors: region-of-interest versus volumetric analysis for quantification of attenuation at CT

Radiology
Hamid ChalianVahid Yaghmai

Abstract

To evaluate the reproducibility of liver tumor attenuation measurement performed by using the routinely used manual region-of-interest (ROI) method and that of measurement performed by using a semiautomated volumetric approach at computed tomography (CT). This HIPAA-compliant retrospective study had institutional review board approval. The requirement for patient informed consent was waived. Attenuation of colon cancer liver metastases in 208 patients was measured on portal venous phase multidetector CT images by using a single ROI, the average measurement in three ROIs on a single section, and with semiautomated segmentation of the entire tumor volume (volumetric attenuation) to evaluate intermethod agreement. Intraobserver and interobserver reproducibility were evaluated in the first 70 patients. Measurements were repeated after 30 days to assess intraobserver reproducibility. Differences between methods were tested by using repeated-measures analysis of variance. Intermethod, intraobserver, and interobserver agreements were tested by using Bland-Altman analysis and the Lin concordance correlation coefficient (ρc). P < .05 was considered to indicate a significant difference. A total of 208 pathologically proven colon cancer h...Continue Reading

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Citations

Jun 26, 2013·AJR. American Journal of Roentgenology·Vahid YaghmaiBachir Taouli
Oct 11, 2013·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Fernanda D Gonzalez-GuindaliniVahid Yaghmai
Mar 19, 2014·Journal of Vascular and Interventional Radiology : JVIR·Caecilia S ReinerHatem Alkadhi
Aug 8, 2015·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Surabhi BajpaiDushyant Sahani
May 8, 2018·European Radiology·Katharina S WinterMelvin D'Anastasi
Oct 27, 2017·AJR. American Journal of Roentgenology·Sahar SemaanBachir Taouli

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